Department of Anesthesiology, Nanjing First Hospital, Nanjing Medical University, Nanjing, 210006, China.
Department of Pain Management, The Affiliated Huai'an Hospital of Xuzhou Medical University and The Second People's Hospital of Huai'an, Huai'an, 223002, China.
J Orthop Surg Res. 2021 Feb 15;16(1):138. doi: 10.1186/s13018-021-02225-8.
Biomechanical comparison of wedge and biconcave deformity of different height restoration after augmentation of osteoporotic vertebral compression fractures was analyzed by three-dimensional finite element analysis (FEA).
Three-dimensional finite element model (FEM) of T11-L2 segment was constructed from CT scan of elderly osteoporosis patient. The von Mises stresses of vertebrae, intervertebral disc, facet joints, displacement, and range of motion (ROM) of wedge and biconcave deformity were compared at four different heights (Genant 0-3 grade) after T12 vertebral augmentation.
In wedge deformity, the stress of T12 decreased as the vertebral height in neutral position, flexion, extension, and left axial rotation, whereas increased sharply in bending at Genant 0; L1 and L2 decreased in all positions excluding flexion of L2, and T11 increased in neutral position, flexion, extension, and right axial rotation at Genant 0. No significant changes in biconcave deformity. The stress of T11-T12, T12-L1, and L1-L2 intervertebral disc gradually increased or decreased under other positions in wedge fracture, whereas L1-L2 no significant change in biconcave fracture. The utmost overall facet joint stress is at Genant 3, whereas there is no significant change under the same position in biconcave fracture. The displacement and ROM of the wedge fracture had ups and downs, while a decline in all positions excluding extension in biconcave fracture.
The vertebral restoration height after augmentation to Genant 0 affects the von Mises stress, displacement, and ROM in wedge deformity, which may increase the risk of fracture, whereas restored or not in biconcave deformity.
通过三维有限元分析(FEA)分析骨质疏松性椎体压缩性骨折增强后不同高度楔形和双凹变形的生物力学比较。
从老年骨质疏松症患者的 CT 扫描中构建 T11-L2 节段的三维有限元模型(FEM)。比较 T12 椎体增强后 4 种不同高度(Genant 0-3 级)下楔形和双凹变形的椎体、椎间盘、小关节、位移和活动范围(ROM)的 von Mises 应力。
在楔形变形中,T12 在中立位、前屈、后伸和左轴向旋转时的椎体高度减小,而在 Genant 0 时则急剧增加;在所有位置中,除 L2 前屈外,L1 和 L2 的应力均减小,而在 Genant 0 中立位、前屈、后伸和右轴向旋转时,T11 增加。双凹变形无明显变化。在楔形骨折中,T11-T12、T12-L1 和 L1-L2 椎间盘的应力在其他位置下逐渐增加或减少,而双凹骨折的 L1-L2 无明显变化。最大的总体小关节应力在 Genant 3,而在双凹骨折的同一位置没有明显变化。楔形骨折的位移和 ROM 有起有落,而双凹骨折除伸展外所有位置均下降。
增强后 Genant 0 的椎体恢复高度会影响楔形变形的 von Mises 应力、位移和 ROM,可能增加骨折风险,而双凹变形则不会。