佩圭罗-洛·普雷斯蒂心电图左心室肥厚标准的短期可重复性。
Short-term repeatability of the peguero-lo presti electrocardiographic left ventricular hypertrophy criteria.
机构信息
Department of Epidemiology, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina.
Department of Epidemiology and Prevention, Epidemiological Cardiology Research Center (EPICARE), Wake Forest School of Medicine, Winston Salem, North Carolina.
出版信息
Ann Noninvasive Electrocardiol. 2021 May;26(3):e12829. doi: 10.1111/anec.12829. Epub 2021 Feb 16.
BACKGROUND
Electrocardiographic left ventricular hypertrophy (ECG-LVH) represents preclinical cardiovascular disease and predicts cardiovascular disease morbidity and mortality. While the newly developed Peguero-Lo Presti ECG-LVH criteria have greater sensitivity for LVH than the Cornell voltage and Sokolow-Lyon criteria, its short-term repeatability is unknown. Therefore, we characterized the short-term repeatability of Peguero-Lo Presti ECG-LVH criteria and evaluate its agreement with Cornell voltage and Sokolow-Lyon ECG-LVH criteria.
METHODS
Participants underwent two resting, standard, 12-lead ECGs at each of two visits one week apart (n = 63). We defined a Peguero-Lo Presti index as a sum of the deepest S wave amplitude in any single lead and lead V (i.e., S + SV ) and defined Peguero-Lo Presti LVH index as ≥ 2,300 µV among women and ≥ 2,800 µV among men. We estimated repeatability as an intraclass correlation coefficient (ICC), agreement as a prevalence-adjusted bias-adjusted kappa coefficient (κ), and precision using 95% confidence intervals (CIs).
RESULTS
The Peguero-Lo Presti index was repeatable: ICC (95% CI) = 0.94 (0.91-0.97). Within-visit agreement of Peguero-Lo Presti LVH was high at the first and second visits: κ (95% CI) = 0.97 (0.91-1.00) and 1.00 (1.00-1.00). Between-visit agreement of the first and second measurements at each visit was comparable: κ (95% CI) = 0.90 (0.80-1.00) and 0.93 (0.85-1.00). Agreement of Peguero-Lo Presti and Cornell or Sokolow-Lyon LVH on any one of the four ECGs was slightly lower: κ (95% CI) = 0.71 (0.54-0.89).
CONCLUSION
The Peguero-Lo Presti index and LVH have excellent repeatability and agreement, which support their use in clinical and epidemiological studies.
背景
心电图左心室肥厚（ECG-LVH）代表临床前心血管疾病，并预测心血管疾病发病率和死亡率。虽然新开发的 Peguero-Lo Presti ECG-LVH 标准比 Cornell 电压和 Sokolow-Lyon 标准对 LVH 的敏感性更高，但它的短期重复性尚不清楚。因此，我们描述了 Peguero-Lo Presti ECG-LVH 标准的短期重复性，并评估了其与 Cornell 电压和 Sokolow-Lyon ECG-LVH 标准的一致性。
方法
参与者在两次间隔一周的访问中，每个访问进行两次静息标准 12 导联心电图检查（n=63）。我们定义 Peguero-Lo Presti 指数为单个导联中最深 S 波振幅之和和导联 V（即 S+SV），并定义女性 Peguero-Lo Presti LVH 指数为≥2300µV，男性为≥2800µV。我们使用 95%置信区间（CI）来估计重复性作为组内相关系数（ICC），一致性作为校正偏倚后的校正后的 Kappa 系数（κ），并使用 95%置信区间（CI）来评估精确度。
结果
Peguero-Lo Presti 指数具有可重复性：ICC（95%CI）=0.94（0.91-0.97）。第一次和第二次就诊时，Peguero-Lo Presti LVH 的就诊内一致性较高：κ（95%CI）=0.97（0.91-1.00）和 1.00（1.00-1.00）。每次就诊时，第一次和第二次测量之间的就诊间一致性相当：κ（95%CI）=0.90（0.80-1.00）和 0.93（0.85-1.00）。任何一次四个心电图中 Peguero-Lo Presti 和 Cornell 或 Sokolow-Lyon LVH 的一致性稍低：κ（95%CI）=0.71（0.54-0.89）。
结论
Peguero-Lo Presti 指数和 LVH 具有极好的重复性和一致性，支持它们在临床和流行病学研究中的应用。
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