儿童和青少年慢性疼痛的流行病学：系统评价更新方案
Epidemiology of chronic pain in children and adolescents: a protocol for a systematic review update.
作者信息
Tutelman Perri R, Langley Charlotte L, Chambers Christine T, Parker Jennifer A, Finley G Allen, Chapman Darlene, Jones Gareth T, Macfarlane Gary J, Marianayagam Justina
机构信息
Department of Psychology and Neuroscience, Dalhousie University, Halifax, Nova Scotia, Canada.
Centre for Pediatric Pain Research, IWK Health Centre, Halifax, Nova Scotia, Canada.
出版信息
BMJ Open. 2021 Feb 16;11(2):e043675. doi: 10.1136/bmjopen-2020-043675.
INTRODUCTION
Chronic pain, defined as persistent or recurring pain or pain lasting longer than 3 months, is a common childhood problem and can profoundly impact children's physical, psychological and social functioning. The last comprehensive systematic review estimating the prevalence of chronic pain in children and adolescents was published in 2011. Since then, the literature on paediatric chronic pain has grown substantially. This manuscript outlines a protocol for an updated systematic review to provide updated estimates of the prevalence of various forms of chronic pain in children and adolescence. The review will also examine the relationship between sociodemographic and psychosocial factors related to chronic pain prevalence.
METHODS AND ANALYSIS
This review will follow Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines. We will search EMBASE, PubMed, CINAHL and PsycINFO for observational studies published in English between 2009 and 2020 reporting population-based estimates of chronic non-disease-related pain prevalence in children or adolescents (age ≤19 years). Two independent reviewers will screen the titles and abstracts retrieved from the search based on predefined eligibility criteria. The full texts of relevant studies will then be assessed by two reviewers. Studies meeting inclusion criteria will be categorised according to the type of pain investigated: headache only, abdominal pain only, back pain only, musculoskeletal pain, combined pain, general pain and other pain. Data will be extracted using customised forms and studies will be assessed for risk of bias using a 10-item tool developed by Hoy (2012). A narrative synthesis will summarise the prevalence estimates of paediatric chronic pain and associated sociodemographic and psychosocial correlates. Meta-analyses and meta-regressions will be performed if the data permit.
ETHICS AND DISSEMINATION
Ethical approval is not required. Findings will be disseminated through publication in an academic journal, presentations at conferences and in various media.
PROSPERO REGISTRATION NUMBER
CRD42020198690.
引言
慢性疼痛被定义为持续性或复发性疼痛，或持续时间超过3个月的疼痛，是儿童常见的问题，会对儿童的身体、心理和社会功能产生深远影响。上一次全面系统回顾估计儿童和青少年慢性疼痛患病率的研究发表于2011年。从那时起，关于儿童慢性疼痛的文献大量增加。本手稿概述了一项更新的系统回顾方案，以提供儿童和青少年各种形式慢性疼痛患病率的最新估计。该回顾还将研究与慢性疼痛患病率相关的社会人口学和心理社会因素之间的关系。
方法与分析
本回顾将遵循系统评价和Meta分析的首选报告项目指南。我们将在EMBASE、PubMed、CINAHL和PsycINFO中检索2009年至2020年期间以英文发表的观察性研究，这些研究报告了基于人群的儿童或青少年（年龄≤19岁）慢性非疾病相关疼痛患病率估计。两名独立评审员将根据预先定义的纳入标准筛选从搜索中检索到的标题和摘要。然后，两名评审员将评估相关研究的全文。符合纳入标准的研究将根据所调查的疼痛类型进行分类：仅头痛、仅腹痛、仅背痛、肌肉骨骼疼痛、混合性疼痛、全身性疼痛和其他疼痛。将使用定制表格提取数据，并使用Hoy（2012年）开发的10项工具评估研究的偏倚风险。叙述性综述将总结儿童慢性疼痛的患病率估计以及相关的社会人口学和心理社会相关性。如果数据允许，将进行Meta分析和Meta回归。
伦理与传播
无需伦理批准。研究结果将通过在学术期刊上发表、在会议上展示以及在各种媒体上传播。
PROSPERO注册号：CRD42020198690。
Zotero 插件