Department of Paediatrics, Division of Pediatric Infectious Diseases, Manipal Hospital, Bangalore, India.
Global Medical Affairs, GSK, Belgium.
Hum Vaccin Immunother. 2022 Dec 31;18(1):1868820. doi: 10.1080/21645515.2020.1868820. Epub 2021 Feb 17.
In the last two decades, outbreaks due to the foodborne hepatitis A virus (HAV) have been frequently reported in India, with adolescents and adults primarily affected. In India, most food handlers are adolescents and young adults who might be exposed to unsatisfactory environmental conditions and poor water quality. This increases the risk of HAV infection and consequently compounds the risk of HAV transmission from food handlers to susceptible populations. Given the shift in hepatitis A endemicity from high to intermediate levels in India, implementing the vaccination of food handlers has become important as it can also contribute to the elimination of hepatitis A in India. This narrative review makes a case for hepatitis A immunization of food handlers in India considering the growing food industry, evolving food culture, and the substantial burden caused by hepatitis A outbreaks.
在过去的二十年中,印度频繁报告了食源性甲型肝炎病毒 (HAV) 爆发,主要影响青少年和成年人。在印度,大多数食品从业人员是青少年和年轻人,他们可能面临不理想的环境条件和较差的水质。这增加了 HAV 感染的风险,从而增加了食品从业人员向易感人群传播 HAV 的风险。鉴于印度甲型肝炎的地方性从高流行水平转变为中流行水平,实施食品从业人员的疫苗接种变得很重要,因为这也有助于在印度消除甲型肝炎。考虑到不断发展的食品工业、不断变化的食品文化以及甲型肝炎爆发带来的巨大负担,本叙述性综述为印度食品从业人员的甲型肝炎免疫接种提供了依据。