靶向金属有机框架纳米平台消除巨噬细胞内的抗生素耐药菌。
Elimination of macrophage-entrapped antibiotic-resistant bacteria by a targeted metal-organic framework-based nanoplatform.
机构信息
Laboratory of Chemical Biology and State Key Laboratory of Rare Earth Resource Utilization, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun, Jilin 130022, China.
出版信息
Chem Commun (Camb). 2021 Mar 18;57(23):2903-2906. doi: 10.1039/d0cc08340b.
PMID:33616152
Abstract
A novel metal-organic framework-based platform was designed and constructed for photosensitizer delivery for the elimination of intracellular antibiotic-resistant bacteria. With the merit of targeting and internalizing ability, the system could kill the stealthy bacteria efficiently under light irradiation.
摘要
设计并构建了一种基于新型金属-有机骨架的平台用于递送电致化学动力学治疗剂以消除细胞内的抗生素耐药菌。该系统具有靶向和内化能力的优势，在光照下可以有效地杀死隐匿性细菌。
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