Department of Critical Care Medicine, Beijing Tiantan Hospital, Capital Medical University, No. 119 South Fourth Ring West Road, Fengtai District, Beijing, 100070, China.
China National Clinical Research Center for Neurological Diseases, Beijing Tiantan Hospital, Capital Medical University, Beijing, 100070, China.
BMC Anesthesiol. 2021 Feb 25;21(1):61. doi: 10.1186/s12871-021-01286-w.
Pain, agitation-sedation and delirium management are crucial elements in the care of critically ill patients. In the present study, we aimed to present the current practice of pain, agitation-sedation and delirium assessments in Chinese intensive care units (ICUs) and investigate the gap between physicians' perception and actual clinical performance.
We sent invitations to the 33 members of the Neuro-Critical Care Committee affiliated with the Chinese Association of Critical Care Physicians. Finally, 24 ICUs (14 general-, 5 neuroscience-, 3 surgical-, and 2 emergency-ICUs) from 20 hospitals participated in this one-day point prevalence study combined with an on-site questionnaire survey. We enrolled adult ICU admitted patients with a length of stay ≥24 h, who were divided into the brain-injured group or non-brain-injured group. The hospital records and nursing records during the 24-h period prior to enrollment were reviewed. Actual evaluations of pain, agitation-sedation and delirium were documented. We invited physicians on-duty during the 24 h prior to the patients' enrollment to complete a survey questionnaire, which contained attitude for importance of pain, agitation-sedation and delirium assessments.
We enrolled 387 patients including 261 (67.4%) brain-injured and 126 (32.6%) non-brain-injured patients. There were 19.9% (95% confidence interval [CI]: 15.9-23.9%) and 25.6% (95% CI: 21.2-29.9%) patients receiving the pain and agitation-sedation scale assessment, respectively. The rates of these two types of assessments were significantly lower in brain-injured patients than non-brain-injured patients (p = 0.003 and < 0.001). Delirium assessment was only performed in three patients (0.8, 95% CI: 0.1-1.7%). In questionnaires collected from 91 physicians, 70.3% (95% CI: 60.8-79.9%) and 82.4% (95% CI: 74.4-90.4%) reported routine use of pain and agitation-sedation scale assessments, respectively. More than half of the physicians (52.7, 95% CI: 42.3-63.2%) reported daily screening for delirium using an assessment scale.
The actual prevalence of pain, agitation-sedation and delirium assessment, especially delirium screening, was suboptimal in Chinese ICUs. There is a gap between physicians' perceptions and actual clinical practice in pain, agitation-sedation and delirium assessments. Our results will prompt further quality improvement projects to optimize the practice of pain, agitation-sedation and delirium management in China.
ClinicalTrials.gov, identifier NCT03975751 . Retrospectively registered on 2 June 2019.
疼痛、躁动-镇静和谵妄管理是危重症患者护理的关键要素。在本研究中,我们旨在介绍中国重症监护病房(ICU)中疼痛、躁动-镇静和谵妄评估的当前实践,并调查医生的感知与实际临床表现之间的差距。
我们向中国危重病医学会神经重症监护委员会的 33 名成员发出了邀请。最终,来自 20 家医院的 24 个 ICU(14 个普通 ICU、5 个神经科学 ICU、3 个外科 ICU 和 2 个急诊 ICU)参与了这项为期一天的患病率研究,并结合现场问卷调查。我们纳入了入住 ICU 时间≥24 小时的成年 ICU 患者,并将其分为脑损伤组和非脑损伤组。回顾了入组前 24 小时的住院病历和护理记录。记录实际的疼痛、躁动-镇静和谵妄评估情况。我们邀请了在患者入组前 24 小时内值班的医生填写一份问卷调查表,其中包含对疼痛、躁动-镇静和谵妄评估重要性的态度。
我们共纳入了 387 名患者,其中 261 名(67.4%)为脑损伤患者,126 名(32.6%)为非脑损伤患者。分别有 19.9%(95%置信区间[CI]:15.9-23.9%)和 25.6%(95% CI:21.2-29.9%)的患者接受了疼痛和躁动-镇静量表评估。这两种评估在脑损伤患者中的发生率明显低于非脑损伤患者(p=0.003 和<0.001)。只有 3 名患者(0.8,95%CI:0.1-1.7%)接受了谵妄评估。在从 91 名医生那里收集的问卷中,分别有 70.3%(95%CI:60.8-79.9%)和 82.4%(95%CI:74.4-90.4%)报告常规使用疼痛和躁动-镇静量表评估。超过一半的医生(52.7,95%CI:42.3-63.2%)报告每天使用评估量表筛查谵妄。
中国 ICU 中疼痛、躁动-镇静和谵妄评估的实际患病率,特别是谵妄筛查,并不理想。在疼痛、躁动-镇静和谵妄评估方面,医生的认知与实际临床实践之间存在差距。我们的研究结果将促使进一步开展质量改进项目,以优化中国疼痛、躁动-镇静和谵妄管理实践。
ClinicalTrials.gov,标识符 NCT03975751。2019 年 6 月 2 日回顾性注册。