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特定的薄芯活动型抗菌髋关节间隔器在扩大转子切开术中导致较高的间隔器骨折率。

High Rates of Spacer Fracture in the Setting of Extended Trochanteric Osteotomy With a Specific Thin-Core Articulating Antibiotic Hip Spacer.

机构信息

Department of Orthopedics, University of Utah, Salt Lake City, UT.

出版信息

J Arthroplasty. 2021 Jun;36(6):2178-2183. doi: 10.1016/j.arth.2021.01.086. Epub 2021 Feb 6.

Abstract

BACKGROUND

Two-stage revision remains the standard of care for prosthetic joint infection after total hip arthroplasty. However, there are substantial complications associated with articulating antibiotic hip spacers. Handmade and molded spacers have been shown to have higher rates of spacer fracture than antibiotic-coated prostheses (ACPs). The aim of this study is to review outcomes with an implant that is often categorized as an ACP spacer, the Zimmer-Biomet StageOne Select Femoral Spacer (ZBSO).

METHODS

A retrospective review was performed of 63 patients who underwent placement of a ZBSO. Patients were compared based on whether or not an extended trochanteric osteotomy (ETO) was performed using Fisher's exact and t-tests.

RESULTS

Five patients were excluded due to lack of follow-up or death shortly after stage 1 surgery, leaving 58 patients. Spacer fracture was noted in 5 of 58 patients (8.6%). Sixteen patients underwent ETO and 25.0% suffered a spacer fracture compared to 2.3% without ETO (odds ratio 13.7, P = .0248). There was no association between patient demographics or ETO length and spacer fracture. Two patients had periprosthetic fractures (3.4%) and 4 had dislocations (6.9%). Forty-nine patients (84.4%) went on to second-stage revision; of those 26.5% failed to clear the infection and required an average of 2.2 additional surgeries.

CONCLUSION

The ZBSO spacer has overall complication rates similar to previously reported spacer series. Although the ZBSO looks like an ACP spacer, in the setting of ETO, it behaves like a molded or handmade spacer with a high rate of spacer fracture (25%) due to the small diameter of the core. This implant should be used with caution in combination with an ETO.

摘要

背景

在全髋关节置换术后,二期翻修仍然是治疗人工关节感染的标准方法。然而,关节抗生素髋 spacer 存在大量并发症。已证明手工制作和模制 spacer 的 spacer 骨折发生率高于抗生素涂层假体 (ACP)。本研究旨在回顾一种常被归类为 ACP spacer 的植入物的结果,即 Zimmer-Biomet StageOne Select 股骨 spacer (ZBSO)。

方法

对 63 例接受 ZBSO 植入的患者进行回顾性分析。Fisher 精确检验和 t 检验比较了是否行延长转子截骨术 (ETO) 的患者。

结果

5 例患者因缺乏随访或 stage1 手术后不久死亡而被排除在外,最终纳入 58 例患者。58 例患者中有 5 例(8.6%)出现 spacer 骨折。16 例行 ETO,25.0%发生 spacer 骨折,而未行 ETO 的为 2.3%(比值比 13.7,P =.0248)。患者人口统计学特征或 ETO 长度与 spacer 骨折之间无关联。2 例患者发生假体周围骨折(3.4%),4 例患者发生脱位(6.9%)。49 例患者(84.4%)进行二期翻修;其中 26.5%未能清除感染,平均需要 2.2 次额外手术。

结论

ZBSO spacer 的总体并发症发生率与之前报道的 spacer 系列相似。尽管 ZBSO 看起来像 ACP spacer,但在 ETO 的情况下,由于核心直径较小,它的行为类似于模制或手工制作的 spacer,具有较高的 spacer 骨折发生率(25%)。在与 ETO 联合使用时,应谨慎使用该植入物。

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