Faculty of Environmental Science, Sai Gon University, Ho Chi Minh City, Vietnam.
Faculty of Pharmacy, Ton Duc Thang University, Ho Chi Minh City, Vietnam.
Nat Prod Res. 2022 Aug;36(15):3865-3871. doi: 10.1080/14786419.2021.1892672. Epub 2021 Mar 3.
Two new phenolic compounds, cristiferides A-B () together with six known compounds, 2,4-dihydroxyphthalide (), lecanoric acid (), orsellinic acid (), 5-chloroorsellinic acid (), methyl haematommate (), and methyl β-orsellinate () were isolated from the lichen (Taylor) Hale (Parmeliaceae). The structures of isolated compounds were identified from its spectroscopic data and by comparison with the literatures. Compounds - and were evaluated for alpha-glucosidase inhibition. Compounds and revealed potent activity with IC values of 72.66 μM and 48.73 μM, respectively.
从地茶(Taylor)Hale(Parmeliaceae)中分离得到两种新的酚类化合物,cristiferides A-B(),以及六种已知化合物:2,4-二羟基邻苯二甲酸酐()、苔黑酚酸()、orsellinic 酸()、5-氯orsellinic 酸()、甲基血根素()和甲基β-orsellinate()。从其光谱数据和与文献的比较中确定了分离化合物的结构。对化合物 - 和 进行了α-葡萄糖苷酶抑制活性评价。化合物 和 表现出较强的活性,IC 值分别为 72.66 μM 和 48.73 μM。