小儿原发性肝肿瘤：诊断要点
Pediatric Primary Hepatic Tumors: Diagnostic Considerations.
作者信息
Lucas Bryony, Ravishankar Sanjita, Pateva Irina
机构信息
Rainbow Babies and Children's Hospital-Department of Pediatrics, University Hospitals Cleveland Medical Center, Cleveland, OH 44106, USA.
Rainbow Babies and Children's Hospital-Department of Pathology, University Hospitals Cleveland Medical Center, Cleveland, OH 44106, USA.
出版信息
Diagnostics (Basel). 2021 Feb 18;11(2):333. doi: 10.3390/diagnostics11020333.
Abstract
The liver is the third most common site of abdominal tumors in children. This review article aims to summarize current evidence surrounding identification and diagnosis of primary hepatic tumors in the pediatric population based upon clinical presentation, epidemiology, and risk factors as well as classical imaging, histopathological, and molecular diagnostic findings. Readers will be able to recognize the features and distinguish between benign and malignant hepatic tumors within different age groups.
摘要
肝脏是儿童腹部肿瘤的第三大常见发病部位。这篇综述文章旨在基于临床表现、流行病学、危险因素以及经典影像学、组织病理学和分子诊断结果，总结围绕儿童原发性肝肿瘤识别与诊断的现有证据。读者将能够识别不同年龄组肝肿瘤的特征，并区分良性和恶性肝肿瘤。
相似文献
1
Pediatric Primary Hepatic Tumors: Diagnostic Considerations.
Diagnostics (Basel). 2021 Feb 18;11(2):333. doi: 10.3390/diagnostics11020333.
2
Tumors of the liver in children.
Surg Oncol. 2007 Nov;16(3):195-203. doi: 10.1016/j.suronc.2007.07.002. Epub 2007 Aug 21.
3
Liver Tumors in Pediatric Patients.
Surg Oncol Clin N Am. 2021 Apr;30(2):253-274. doi: 10.1016/j.soc.2020.11.006.
4
Update on the Pathology of Pediatric Liver Tumors: A Pictorial Review.
Diagnostics (Basel). 2023 Nov 24;13(23):3524. doi: 10.3390/diagnostics13233524.
5
Primary mesenchymal liver tumors of childhood.
Semin Diagn Pathol. 2017 Mar;34(2):201-207. doi: 10.1053/j.semdp.2016.12.016. Epub 2016 Dec 23.
6
Fetal and neonatal hepatic tumors.
J Pediatr Surg. 2007 Nov;42(11):1797-803. doi: 10.1016/j.jpedsurg.2007.07.047.
7
Magnetic resonance imaging of pediatric liver tumors.
Pediatr Radiol. 2022 Feb;52(2):177-188. doi: 10.1007/s00247-021-05058-z. Epub 2021 Apr 14.
8
[Hepatic tumors in childhood: experience on 245 tumors and review of literature].
Ann Pathol. 2004 Dec;24(6):536-55. doi: 10.1016/s0242-6498(04)94017-5.
9
Primary liver neoplasms: MR imaging with pathologic correlation.
Radiographics. 1994 May;14(3):459-82. doi: 10.1148/radiographics.14.3.8066263.
10
Pathology of pediatric liver tumors, a single center experience from south of Iran.
Indian J Pathol Microbiol. 2010 Jul-Sep;53(3):422-6. doi: 10.4103/0377-4929.68258.
引用本文的文献
1
Imaging insights into pediatric liver masses: A comprehensive minireview for hepatology practice.
World J Hepatol. 2025 Aug 27;17(8):107041. doi: 10.4254/wjh.v17.i8.107041.
2
Isolated Gamma-Glutamyl Transferase Elevation in an Asymptomatic Adolescent: An Unusual Presentation of Focal Nodular Hyperplasia.
Cureus. 2025 Jul 16;17(7):e88050. doi: 10.7759/cureus.88050. eCollection 2025 Jul.
3
Congenital focal nodular hyperplasia-like lesion mimicking hepatoblastoma: anecdotal but plausible.
World J Pediatr Surg. 2025 Apr 14;8(2):e000980. doi: 10.1136/wjps-2024-000980. eCollection 2025.
4
Segmental atrophy of the liver in a child: a case description and literature analysis.
Quant Imaging Med Surg. 2025 Jan 2;15(1):1051-1054. doi: 10.21037/qims-24-1324. Epub 2024 Dec 11.
5
Abdominopelvic tumors of infancy: a pictorial essay.
Pediatr Radiol. 2025 Mar;55(3):437-458. doi: 10.1007/s00247-024-06147-5. Epub 2025 Jan 11.
6
Abdominal pain and distension in a 4-years-old child revealing an hepatoblastoma.
Radiol Case Rep. 2024 Sep 12;19(12):5804-5808. doi: 10.1016/j.radcr.2024.07.185. eCollection 2024 Dec.
7
When the Belly Looks Okay but Is Actually Not: A Case of Hepatoblastoma in a Well-Appearing Child.
Cureus. 2024 Jun 1;16(6):e61480. doi: 10.7759/cureus.61480. eCollection 2024 Jun.
8
Accuracy of contrast-enhanced CT in liver neoplasms in children under 2 years age.
Pediatr Radiol. 2024 Nov;54(12):1946-1955. doi: 10.1007/s00247-024-05958-w. Epub 2024 Jun 3.
9
Hepatoblastoma Presenting as Rapidly Progressive Abdominal Mass in a Toddler-A Case Report.
Indian J Surg Oncol. 2024 May;15(Suppl 2):355-358. doi: 10.1007/s13193-024-01887-0. Epub 2024 Feb 2.
10
Mesenchymal hepatic hamartoma: A rare case of severe respiratory distress in a neonate.
Clin Case Rep. 2024 Mar 13;12(3):e8562. doi: 10.1002/ccr3.8562. eCollection 2024 Mar.
本文引用的文献
1
Histopathological Variants of Hepatocellular Carcinomas: an Update According to the 5th Edition of the WHO Classification of Digestive System Tumors.
J Liver Cancer. 2020 Mar;20(1):17-24. doi: 10.17998/jlc.20.1.17. Epub 2020 Mar 31.
2
Undifferentiated embryonal sarcoma of the liver: A rare hepatic tumor and its related characteristic radiological features.
Radiol Case Rep. 2021 Jan 7;16(3):646-650. doi: 10.1016/j.radcr.2020.12.017. eCollection 2021 Mar.
3
Screening for infantile hepatic hemangioma in patients with cutaneous infantile hemangioma: A multicenter prospective study.
J Am Acad Dermatol. 2021 May;84(5):1378-1384. doi: 10.1016/j.jaad.2020.11.062. Epub 2020 Dec 4.
4
Undifferentiated embryonal sarcoma of the liver: Clinical characteristics and outcomes.
World J Clin Cases. 2020 Oct 26;8(20):4763-4772. doi: 10.12998/wjcc.v8.i20.4763.
5
Pediatric hepatic vascular tumors.
Semin Pediatr Surg. 2020 Oct;29(5):150970. doi: 10.1016/j.sempedsurg.2020.150970. Epub 2020 Sep 16.
6
Case Report: Hepatic Adenoma in a Child With a Congenital Extrahepatic Portosystemic Shunt.
Front Pediatr. 2020 Aug 25;8:501. doi: 10.3389/fped.2020.00501. eCollection 2020.
7
Focal nodular hyperplasia masquerading as malignancy in an infant with elevated alpha-fetoprotein: A case report with literature review.
Clin Imaging. 2021 Jan;69:228-232. doi: 10.1016/j.clinimag.2020.08.026. Epub 2020 Aug 27.
8
Contrast-Enhanced Ultrasound for the Characterization of Infantile Hepatic Hemangioma in Premature Neonate.
Cureus. 2020 Aug 5;12(8):e9580. doi: 10.7759/cureus.9580.
9
Hepatic mesenchymal hamartoma: An uncommon but important paediatric diagnosis.
SA J Radiol. 2020 Jul 27;24(1):1891. doi: 10.4102/sajr.v24i1.1891. eCollection 2020.
10
Computed tomography imaging and clinical features of congenital hepatoblastoma: A retrospective analysis.
Medicine (Baltimore). 2020 Jul 31;99(31):e21174. doi: 10.1097/MD.0000000000021174.
Zotero 插件