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重新考虑在全膝关节置换术中常规使用止血带。

Time to reconsider the routine use of tourniquets in total knee arthroplasty surgery.

机构信息

Warwick Clinical Trials Unit, University of Warwick, Coventry, UK.

Trauma and Orthopaedic Surgery, University Hospitals Coventry and Warwickshire NHS Trust, Coventry, UK.

出版信息

Bone Joint J. 2021 May;103-B(5):830-839. doi: 10.1302/0301-620X.103B.BJJ-2020-1926.R1. Epub 2021 Mar 8.

Abstract

AIMS

Many surgeons choose to perform total knee arthroplasty (TKA) surgery with the aid of a tourniquet. A tourniquet is a device that fits around the leg and restricts blood flow to the limb. There is a need to understand whether tourniquets are safe, and if they benefit, or harm, patients. The aim of this study was to determine the benefits and harms of tourniquet use in TKA surgery.

METHODS

We searched MEDLINE, EMBASE, Cochrane Central Register of Controlled trials, and trial registries up to 26 March 2020. We included randomized controlled trials (RCTs), comparing TKA with a tourniquet versus without a tourniquet. Outcomes included: pain, function, serious adverse events (SAEs), blood loss, implant stability, duration of surgery, and length of hospital stay.

RESULTS

We included 41 RCTs with 2,819 participants. SAEs were significantly more common in the tourniquet group (53/901 vs 26/898, tourniquet vs no tourniquet respectively) (risk ratio 1.73 (95% confidence interval (CI) 1.10 to 2.73). The mean pain score on the first postoperative day was 1.25 points higher (95% CI 0.32 to 2.19) in the tourniquet group. Overall blood loss did not differ between groups (mean difference 8.61 ml; 95% CI -83.76 to 100.97). The mean length of hospital stay was 0.34 days longer in the group that had surgery with a tourniquet (95% CI 0.03 to 0.64) and the mean duration of surgery was 3.7 minutes shorter (95% CI -5.53 to -1.87).

CONCLUSION

TKA with a tourniquet is associated with an increased risk of SAEs, pain, and a marginally longer hospital stay. The only finding in favour of tourniquet use was a shorter time in theatre. The results make it difficult to justify the routine use of a tourniquet in TKA surgery. Cite this article:  2021;103-B(5):830-839.

摘要

目的

许多外科医生选择在止血带的辅助下进行全膝关节置换术(TKA)。止血带是一种环绕腿部并限制肢体血流的装置。需要了解止血带是否安全,以及它是否对患者有益还是有害。本研究的目的是确定 TKA 手术中使用止血带的益处和危害。

方法

我们检索了 MEDLINE、EMBASE、Cochrane 对照试验中心注册库和试验登记处,截至 2020 年 3 月 26 日。我们纳入了比较 TKA 中使用止血带与不使用止血带的随机对照试验(RCT)。结局包括:疼痛、功能、严重不良事件(SAE)、失血量、植入物稳定性、手术时间和住院时间。

结果

我们纳入了 41 项 RCT,共 2819 名参与者。SAE 在止血带组更为常见(53/901 比 26/898,分别为止血带组和无止血带组)(风险比 1.73(95%置信区间(CI)1.10 至 2.73)。止血带组术后第一天的平均疼痛评分高 1.25 分(95%CI 0.32 至 2.19)。两组总体失血量无差异(平均差值 8.61ml;95%CI-83.76 至 100.97)。使用止血带的手术组住院时间平均延长 0.34 天(95%CI 0.03 至 0.64),手术时间平均缩短 3.7 分钟(95%CI-5.53 至-1.87)。

结论

TKA 中使用止血带与 SAE、疼痛增加以及住院时间延长有关。唯一支持使用止血带的发现是手术时间更短。这些结果使得难以证明 TKA 手术中常规使用止血带是合理的。

引用

2021;103-B(5):830-839.

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bec1/8091001/354a9e7e3a34/BJJ-103B-830-g0001.jpg

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