Population Health Sciences Institute, Newcastle University, Newcastle upon Tyne, UK.
Faculty of Health and Life Sciences, Northumbria University, Newcastle upon Tyne, UK.
Cochrane Database Syst Rev. 2021 Mar 16;3(3):CD012823. doi: 10.1002/14651858.CD012823.pub2.
Parental substance use is a substantial public health and safeguarding concern. There have been a number of trials of interventions relating to substance-using parents that have sought to address this risk factor, with potential outcomes for parent and child.
To assess the effectiveness of psychosocial interventions in reducing parental substance use (alcohol and/or illicit drugs, excluding tobacco).
We searched the following databases from their inception to July 2020: the Cochrane Drugs and Alcohol Group Specialised Register; CENTRAL; MEDLINE; Embase; PsycINFO; CINAHL; Applied Social Science (ASSIA); Sociological Abstracts; Social Science Citation Index (SSCI), Scopus, ClinicalTrials.gov, WHO ICTRP, and TRoPHI. We also searched key journals and the reference lists of included papers and contacted authors publishing in the field.
We included data from trials of complex psychosocial interventions targeting substance use in parents of children under the age of 21 years. Studies were only included if they had a minimum follow-up period of six months from the start of the intervention and compared psychosocial interventions to comparison conditions. The primary outcome of this review was a reduction in the frequency of parental substance use.
We used standard methodological procedures expected by Cochrane.
We included 22 unique studies with a total of 2274 participants (mean age of parents ranged from 26.3 to 40.9 years), examining 24 experimental interventions. The majority of studies intervened with mothers only (n = 16; 73%). Heroin, cocaine, and alcohol were the most commonly reported substances used by participants. The interventions targeted either parenting only (n = 13; 59%); drug and alcohol use only (n = 5; 23%); or integrated interventions which addressed both (n = 6; 27%). Half of the studies (n = 11; 50%) compared the experimental intervention to usual treatment. Other comparison groups were minimal intervention, attention controls, and alternative intervention. Eight of the included studies reported data relating to our primary outcome at 6- and/or 12-month follow-up and were included in a meta-analysis. We investigated intervention effectiveness separately for alcohol and drugs. Studies were found to be mostly at low or unclear risk for all 'Risk of bias' domains except blinding of participants and personnel and outcome assessment. We found moderate-quality evidence that psychosocial interventions are probably more effective at reducing the frequency of parental alcohol misuse than comparison conditions at 6-month (mean difference (MD) -0.32, 95% confidence interval (CI) -0.51 to -0.13; 6 studies, 475 participants) and 12-month follow-up (standardised mean difference (SMD) -0.25, 95% CI -0.47 to -0.03; 4 studies, 366 participants). We found a significant reduction in frequency of use at 12 months only (SMD -0.21, 95% CI -0.41 to -0.01; 6 studies, 514 participants, moderate-quality evidence). We examined the effect of the intervention type. We found low-quality evidence that psychosocial interventions targeting substance use only may not reduce the frequency of alcohol (6 months: SMD -0.35, 95% CI -0.86 to 0.16; 2 studies, 89 participants and 12 months: SMD -0.09, 95% CI -0.86 to 0.61; 1 study, 34 participants) or drug use (6 months: SMD 0.01, 95% CI -0.42 to 0.44; 2 studies; 87 participants and 12 months: SMD -0.08, 95% CI -0.81 to 0.65; 1 study, 32 participants). A parenting intervention only, without an adjunctive substance use component, may not reduce frequency of alcohol misuse (6 months: SMD -0.21, 95% CI -0.46 to 0.04, 3 studies; 273 participants, low-quality evidence and 12 months: SMD -0.11, 95% CI -0.64 to 0.41; 2 studies; 219 participants, very low-quality evidence) or frequency of drug use (6 months: SMD 0.10, 95% CI -0.11 to 0.30; 4 studies; 407 participants, moderate-quality evidence and 12 months: SMD -0.13, 95% CI -0.52 to 0.26; 3 studies; 351 participants, very low-quality evidence). Parents receiving integrated interventions which combined both parenting- and substance use-targeted components may reduce alcohol misuse with a small effect size (6 months: SMD -0.56, 95% CI -0.96 to -0.16 and 12 months: SMD -0.42, 95% CI -0.82 to -0.03; 2 studies, 113 participants) and drug use (6 months: SMD -0.39, 95% CI -0.75 to -0.03 and 12 months: SMD -0.43, 95% CI -0.80 to -0.07; 2 studies, 131 participants). However, this evidence was of low quality. Psychosocial interventions in which the child was present in the sessions were not effective in reducing the frequency of parental alcohol or drug use, whilst interventions that did not involve children in any of the sessions were found to reduce frequency of alcohol misuse (6 months: SMD -0.47, 95% CI -0.76 to -0.18; 3 studies, 202 participants and 12 months: SMD -0.34, 95% CI -0.69 to 0.00; 2 studies, 147 participants) and drug use at 12-month follow-up (SMD -0.34, 95% CI -0.69 to 0.01; 2 studies, 141 participants). The quality of this evidence was low. Interventions appeared to be more often beneficial for fathers than for mothers. We found low- to very low-quality evidence of a reduction in frequency of alcohol misuse for mothers at six months only (SMD -0.27, 95% CI -0.50 to -0.04; 4 studies, 328 participants), whilst in fathers there was a reduction in frequency of alcohol misuse (6 months: SMD -0.43, 95% CI -0.78 to -0.09; 2 studies, 147 participants and 12 months: SMD -0.34, 95% CI -0.69 to 0.00; 2 studies, 147 participants) and drug use (6 months: SMD -0.31, 95% CI -0.66 to 0.04; 2 studies, 141 participants and 12 months: SMD -0.34, 95% CI -0.69 to 0.01; 2 studies, 141 participants).
AUTHORS' CONCLUSIONS: We found moderate-quality evidence that psychosocial interventions probably reduce the frequency at which parents use alcohol and drugs. Integrated psychosocial interventions which combine parenting skills interventions with a substance use component may show the most promise. Whilst it appears that mothers may benefit less than fathers from intervention, caution is advised in the interpretation of this evidence, as the interventions provided to mothers alone typically did not address their substance use and other related needs. We found low-quality evidence from few studies that interventions involving children are not beneficial.
父母的物质使用是一个重大的公共卫生和保障问题。已经有许多针对有物质使用问题的父母的干预措施试验,旨在解决这一风险因素,并对父母和孩子产生潜在影响。
评估心理社会干预措施在减少父母物质使用(酒精和/或非法药物,不包括烟草)方面的有效性。
我们从成立到 2020 年 7 月检索了以下数据库: Cochrane 药物和酒精组专业注册库;CENTRAL;MEDLINE;Embase;PsycINFO;CINAHL;应用社会科学(ASSIA);社会学文摘;社会科学引文索引(SSCI),Scopus,临床试验.gov,世界卫生组织国际临床试验注册平台(WHO ICTRP)和 TRoPHI。我们还检索了重点期刊和纳入文献的参考文献,并联系了该领域发表论文的作者。
我们纳入了针对 21 岁以下儿童父母的物质使用进行复杂心理社会干预的试验数据。只有那些随访期至少为干预开始后 6 个月且将心理社会干预与对照条件进行比较的研究才被纳入。本综述的主要结果是减少父母物质使用的频率。
我们使用了 Cochrane 预期的标准方法学程序。
我们纳入了 22 项独特的研究,共 2274 名参与者(父母的平均年龄范围为 26.3 至 40.9 岁),研究了 24 项实验性干预措施。大多数研究只干预了母亲(n=16;73%)。参与者最常报告使用的物质是海洛因、可卡因和酒精。干预措施要么只针对育儿(n=13;59%),要么只针对药物和酒精使用(n=5;23%),要么针对两者的综合干预(n=6;27%)。一半的研究(n=11;50%)将实验干预与常规治疗进行了比较。其他对照组是最小干预、注意力控制和替代干预。纳入的 8 项研究在 6 个月和/或 12 个月的随访中报告了与我们的主要结局相关的数据,并被纳入了一项荟萃分析。我们分别研究了酒精和药物使用的干预效果。除了参与者和人员的盲法以及结局评估之外,我们发现除了参与者和人员的盲法以及结局评估之外,大多数研究在所有“偏倚风险”领域都被认为是低风险或不确定风险。我们发现中等质量的证据表明,心理社会干预可能更有效地减少父母酗酒的频率,与 6 个月(平均差异(MD)-0.32,95%置信区间(CI)-0.51 至-0.13;6 项研究,475 名参与者)和 12 个月随访(标准化均数差异(SMD)-0.25,95%置信区间(CI)-0.47 至-0.03;4 项研究,366 名参与者)时的比较条件相比。我们仅在 12 个月时发现了频率的显著降低(SMD-0.21,95%置信区间-0.41 至-0.01;6 项研究,514 名参与者,中等质量证据)。我们检查了干预类型的效果。我们发现低质量的证据表明,仅针对物质使用的心理社会干预可能不会减少酒精(6 个月:SMD-0.35,95%置信区间-0.86 至 0.16;2 项研究,89 名参与者和 12 个月:SMD-0.09,95%置信区间-0.86 至 0.61;1 项研究,34 名参与者)或药物使用(6 个月:SMD 0.01,95%置信区间-0.42 至 0.44;2 项研究;87 名参与者和 12 个月:SMD-0.08,95%置信区间-0.81 至 0.65;1 项研究,32 名参与者)的频率。仅针对育儿的干预措施,不包括物质使用成分,可能不会减少酒精滥用的频率(6 个月:SMD-0.21,95%置信区间-0.46 至 0.04,3 项研究;273 名参与者,低质量证据和 12 个月:SMD-0.11,95%置信区间-0.64 至 0.41;2 项研究;219 名参与者,极低质量证据)或药物使用频率(6 个月:SMD 0.10,95%置信区间-0.11 至 0.30;4 项研究;407 名参与者,中等质量证据和 12 个月:SMD-0.13,95%置信区间-0.52 至 0.26;3 项研究;351 名参与者,极低质量证据)。接受结合了育儿和物质使用目标的综合干预措施的父母可能会减少酒精滥用,效果较小(6 个月:SMD-0.56,95%置信区间-0.96 至-0.16 和 12 个月:SMD-0.42,95%置信区间-0.82 至-0.03;2 项研究,113 名参与者)和药物使用(6 个月:SMD-0.39,95%置信区间-0.75 至-0.03 和 12 个月:SMD-0.43,95%置信区间-0.80 至-0.07;2 项研究,131 名参与者)。然而,这一证据质量较低。在有孩子参加的会议中,心理社会干预对减少父母酒精或药物使用频率没有效果,而没有让孩子参加任何会议的干预措施则发现减少了酒精滥用频率(6 个月:SMD-0.47,95%置信区间-0.76 至-0.18;3 项研究,202 名参与者和 12 个月:SMD-0.34,95%置信区间-0.69 至 0.00;2 项研究,147 名参与者)和药物使用(12 个月:SMD-0.34,95%置信区间-0.69 至 0.01;2 项研究,141 名参与者)。该证据的质量较低。干预措施似乎对父亲比对母亲更有益。我们发现低至极低质量的证据表明,母亲在六个月时酒精滥用频率降低(SMD-0.27,95%置信区间-0.50 至-0.04;4 项研究,328 名参与者),而父亲的酒精滥用频率降低(6 个月:SMD-0.43,95%置信区间-0.78 至-0.09;2 项研究,147 名参与者和 12 个月:SMD-0.34,95%置信区间-0.69 至 0.00;2 项研究,147 名参与者)和药物使用(6 个月:SMD-0.31,95%置信区间-0.66 至 0.04;2 项研究,141 名参与者和 12 个月:SMD-0.34,95%置信区间-0.69 至 0.01;2 项研究,141 名参与者)。
我们发现中等质量的证据表明,心理社会干预可能会减少父母饮酒和使用药物的频率。结合了育儿技能干预和物质使用成分的综合心理社会干预可能最有希望。虽然母亲可能从干预中获益不如父亲多,但在解释这一证据时要谨慎,因为仅针对母亲的干预措施通常没有解决她们的物质使用和其他相关需求。我们发现来自少数研究的低质量证据表明,涉及儿童的干预措施并不有益。