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甲状旁腺脂肪瘤:一种罕见实体的特殊性——病例报告及文献复习

Parathyroid lipoadenoma: The particularities of a rare entity a case report and review of the literature.

作者信息

Mennouni Mohamed Amine, Oukessou Youssef, El Bouhmadi Khadija, Rouadi Sami, Abada Redallah Larbi, Mahtar Mohamed

机构信息

Department of Otolaryngology, Head and Neck Surgery, 20 August 1953 Hospital, Casablanca, Morocco.

Department of Otolaryngology, Head and Neck Surgery, 20 August 1953 Hospital, Casablanca, Morocco.

出版信息

Int J Surg Case Rep. 2021 Feb;79:455-458. doi: 10.1016/j.ijscr.2021.01.091. Epub 2021 Jan 28.

DOI:10.1016/j.ijscr.2021.01.091
PMID:33757261
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7851336/
Abstract

Parathyroid lipoadenoma is a rare and anusual cause of primary hyperparathyroidism. The clinical presentation usually resembles other causes of primary hyperparathyroidism and the imaging is not always contributory considering its location. However, the histologic criteria are specific. We present a case that supplements and supports the rare literature data concerning the clinical and therapeutic aspects of parathyroid lipoadenoma. The case is about a 73 years old female with a right inferior parathyroid lipoadenoma that caused biological primary hyperparathyroidism. Initially followed and treated in Rheumatology department for hypercalcemia and osteoporosis, she was sent to our structure to diagnose and possibly treat the causal etiology. After non-contributory clinical examination and ultrasound imaging, the tumor was diagnosed in the cervical CT scan. The patient underwent successful surgical removal of the lipoadenoma, confirmed postoperatively on histological analysis. The follow up showed rapid normalization of the parathormon level. Even if it's a rare condition, the diagnosis of lipoadenoma should always be considered in front of primary hyperparathyroidism with a parathyroid lesion.

摘要

甲状旁腺脂肪瘤是原发性甲状旁腺功能亢进症的一种罕见且特殊的病因。其临床表现通常与原发性甲状旁腺功能亢进症的其他病因相似,考虑到其位置,影像学检查并不总是有帮助。然而,组织学标准是明确的。我们报告一例病例,补充并支持了关于甲状旁腺脂肪瘤临床和治疗方面的罕见文献资料。该病例为一名73岁女性,患有右下甲状旁腺脂肪瘤,导致生物性原发性甲状旁腺功能亢进症。最初因高钙血症和骨质疏松症在风湿科接受随访和治疗,后被转至我们科室以诊断并可能治疗病因。经过无诊断价值的临床检查和超声成像后,在颈部CT扫描中诊断出肿瘤。患者成功接受了脂肪瘤切除术,术后组织学分析得以证实。随访显示甲状旁腺激素水平迅速恢复正常。即使这是一种罕见疾病,但在原发性甲状旁腺功能亢进症伴有甲状旁腺病变的情况下,始终应考虑脂肪瘤的诊断。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c020/7851336/11de961bf63d/gr4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c020/7851336/7300833dbefd/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c020/7851336/55dbd9e88372/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c020/7851336/2cecb2b38828/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c020/7851336/11de961bf63d/gr4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c020/7851336/7300833dbefd/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c020/7851336/55dbd9e88372/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c020/7851336/2cecb2b38828/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c020/7851336/11de961bf63d/gr4.jpg

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本文引用的文献

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Int J Surg. 2020 Dec;84:226-230. doi: 10.1016/j.ijsu.2020.10.034. Epub 2020 Nov 9.
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A rare cause of primary hyperparathyroidism: Parathyroid lipoadenoma.原发性甲状旁腺功能亢进症的一种罕见病因:甲状旁腺脂肪瘤。
Auris Nasus Larynx. 2018 Dec;45(6):1245-1248. doi: 10.1016/j.anl.2018.05.001. Epub 2018 May 16.
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Parathyroid Lipoadenoma: A Rare Entity.甲状旁腺脂肪瘤:一种罕见的实体。
原发性甲状旁腺功能亢进症与乳腺癌骨转移鉴别诊断的挑战
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