Department of Pediatrics, National Taiwan University Children's Hospital and College of Medicine, Taipei, Taiwan.
Department of Surgery, National Taiwan University Hospital and College of Medicine, Taipei, Taiwan.
Pediatr Crit Care Med. 2021 Aug 1;22(8):733-742. doi: 10.1097/PCC.0000000000002715.
Medical advances and the National Health Insurance coverage in Taiwan mean that mortality in the PICU is low. This study describes change in modes of death and end-of-life care in a single center, 2011-2017.
Multidisciplinary PICU in a tertiary referral Children's Hospital in Taiwan.
There were 316 deaths in PICU patients.
Palliative care consultation in the PICU service occurred after the 2013 "Hospice Palliative Care Act" revision.
In the whole cohort, 22 of 316 patients (7%) were determined as "death by neurologic criteria". There were 94 of 316 patients (30%) who had an event needing cardiopulmonary resuscitation within 24 hours of death: 17 of these patients (17/94; 18%) died after failed cardiopulmonary resuscitation without a do-not-resuscitate order, and the other 77 of 94 patients (82%) had a do-not-resuscitate order after cardiopulmonary resuscitation. Overall, there were 200 of 316 patients (63%) who had a do-not-resuscitate order and were entered into the palliative program: 169 of 200 (85%) died after life-sustaining treatment was limited, and the other 31 of 200 (15%) died after life-sustaining treatment was withdrawn. From 2011 to 2017, the time-trend in end-of-life care showed the following associations: 1) a decrease in PICU mortality utilization rate, from 22% to 7% (p < 0.001); 2) a decrease in use of catecholamine infusions after do-not-resuscitate consent, from 87% to 47% (p = 0.001), in patients having limitation in life-sustaining treatment; and 3) an increase in withdrawal of life-sustaining treatment, from 4% to 31% (p < 0.001).
In our practice in a single PICU-center in Taiwan, we have seen that the integration of a palliative care consultation service, developed after the revision of a national "Palliative Care Act," was associated with increased willingness to accept withdrawal of life-sustaining treatment and a lowered PICU care intensity at the end-of-life.
医学进步和台湾全民健康保险覆盖意味着儿科重症监护病房(PICU)的死亡率较低。本研究描述了 2011 年至 2017 年期间,在一家三级转诊儿童医院的单一中心,死亡模式和临终关怀的变化。
台湾一家儿童医院的多学科 PICU。
PICU 患者中有 316 人死亡。
2013 年《安宁缓和医疗条例》修订后,在 PICU 服务中提供姑息治疗咨询。
在整个队列中,316 名患者中有 22 名(7%)被确定为“神经学标准死亡”。316 名患者中有 94 名(30%)在死亡前 24 小时内发生需要心肺复苏的事件:其中 17 名患者(17/94;18%)在没有拒绝心肺复苏的情况下心肺复苏失败后死亡,94 名患者中有 77 名(77/94)在心肺复苏后下达了拒绝心肺复苏的医嘱。总体而言,316 名患者中有 200 名(63%)下达了拒绝心肺复苏的医嘱,并进入姑息治疗计划:200 名患者中有 169 名(85%)在限制生命维持治疗后死亡,200 名患者中有 31 名(15%)在停止生命维持治疗后死亡。2011 年至 2017 年,临终关怀的时间趋势显示出以下关联:1)PICU 死亡率使用率从 22%降至 7%(p<0.001);2)在限制生命维持治疗的患者中,拒绝心肺复苏同意后使用去甲肾上腺素输注的比例从 87%降至 47%(p=0.001);3)停止生命维持治疗的比例从 4%增加到 31%(p<0.001)。
在台湾一家 PICU 中心的实践中,我们发现姑息治疗咨询服务的整合与接受停止生命维持治疗的意愿增加以及临终关怀时 PICU 护理强度降低有关,该服务是在国家《缓和医疗法》修订后发展起来的。