Sousa Helena B A, Martins Catarina S M, Prior João A V
LAQV, REQUIMTE, Laboratory of Applied Chemistry, Department of Chemical Sciences, Faculty of Pharmacy, University of Porto, Rua de Jorge Viterbo Ferreira n. 228, 4050-313 Porto, Portugal.
Nanomaterials (Basel). 2021 Mar 1;11(3):611. doi: 10.3390/nano11030611.
Carbon quantum dots (CQDs) have started to emerge as candidates for application in cell imaging, biosensing, and targeted drug delivery, amongst other research fields, due to their unique properties. Those applications are possible as the CQDs exhibit tunable fluorescence, biocompatibility, and a versatile surface. This review aims to summarize the recent development in the field of CQDs research, namely the latest synthesis progress concerning materials/methods, surface modifications, characterization methods, and purification techniques. Furthermore, this work will systematically explore the several applications CQDs have been subjected to, such as bioimaging, fluorescence sensing, and cancer/gene therapy. Finally, we will briefly discuss in the concluding section the present and future challenges, as well as future perspectives and views regarding the emerging paradigm that is the CQDs research field.
碳量子点(CQDs)因其独特的性质,已开始在细胞成像、生物传感和靶向药物递送等研究领域崭露头角,成为潜在的应用材料。这些应用之所以可行,是因为碳量子点具有可调谐荧光、生物相容性和多功能表面。本综述旨在总结碳量子点研究领域的最新进展,即材料/方法、表面修饰、表征方法和纯化技术方面的最新合成进展。此外,本文将系统地探讨碳量子点的几种应用,如生物成像、荧光传感以及癌症/基因治疗。最后,我们将在结论部分简要讨论当前和未来面临的挑战,以及关于碳量子点研究领域这一新兴范式的未来前景和观点。