Escuela Técnica Superior de Ingenieros de Telecomunicación, Universidad Politécnica de Madrid, 28040 Madrid, Spain.
CTB (CTB-UPM) Centro de Tecnología Biomédica, Universidad Politécnica de Madrid, 28223 Pozuelo de Alarcón, Spain.
Int J Mol Sci. 2021 Mar 31;22(7):3642. doi: 10.3390/ijms22073642.
Many exogenous and endogenous risk factors have been proposed as precursors of brain tumors, including the exposure to non-ionizing electromagnetic fields. Nevertheless, there is still a debate among the scientific community about the hazard of the effects produced by non-ionizing radiation (NIR) because conflicting results have been found (number of articles reviewed >50). For that reason, to provide new evidence on the possible effects produced by exposure to NIR, we performed different studies with several combinations of extremely low frequencies, times, and field intensities in tumoral and non-tumoral cells. The results of our studies showed that cell viability was frequency dependent in glioblastoma cells. In fact, our results revealed that a frequency of 30 Hz-or even other frequencies close to 30 Hz-could constitute a window frequency determinant of the cellular response in tumoral and non-tumoral cells.
许多外源和内源风险因素被认为是脑瘤的前兆,包括接触非电离电磁辐射。然而,科学界仍然存在关于非电离辐射(NIR)效应危害的争论,因为已经发现了相互矛盾的结果(审查的文章数量>50)。因此,为了提供关于暴露于 NIR 可能产生的影响的新证据,我们在肿瘤和非肿瘤细胞中进行了不同的研究,这些研究采用了不同的极低频、时间和场强组合。我们研究的结果表明,神经胶质瘤细胞的细胞活力与频率有关。事实上,我们的结果表明,频率为 30Hz 甚至接近 30Hz 的其他频率可能构成肿瘤和非肿瘤细胞中细胞反应的决定窗频率。