Wataganara Tuangsit, Trigo Lucas, Lapa Denise Araujo
Division of Maternal Fetal Medicine, Department of Obstetrics, Faculty of Medicine, Siriraj Hospital, Mahidol University, Bangkok, Thailand.
Hospital Israelita Albert Einstein, Fetal Therapy Program, São Paulo, SP, Brazil.
J Perinat Med. 2021 Apr 5. doi: 10.1515/jpm-2020-0591.
Skin-over-biocellulose for Antenatal Fetoscopic Repair (SAFER) is a recently developed technique for fully percutaneous fetoscopic repair of myelomeningocele. The formation of a neo-dura mater triggered by the use of a biocellulose patch over the placode obviates the need of primary repair of fetal dura mater, and seems to further improve neurodevelopmental outcome. Insufflation of humidified carbon dioxide into the amniotic cavity requires proper training and a different equipment set from those used in the classic "under-water" fetoscopy. To shorten the learning curve of novice teams, we have developed a structured training course encompassing three critical steps: (1) visiting the proctor center, (2) selection of the first case, and (3) on-site training of the surgical team. Upon the site arrival, there will be: (1) theoretical lecture for all specialists involved in the fetal care, (2) simulation training, and (3) surgical proctoring. Proctor team can take over the surgery if the local team cannot complete. This training course has been successfully used in five different countries: Israel, Chile, Italy, USA and England and all local teams are already performing surgeries solo without any failures or maternal morbidity. Teaching new procedures in fetal medicine is challenging, because of the small number of candidate cases, and the direct relation of good outcomes and the number of cases operated. This proposed training modules may be adopted by other teams that want to embark on this type of novel minimally invasive treatment.
用于产前胎儿镜修复的皮肤覆盖生物纤维素(SAFER)是一种最近开发的用于完全经皮胎儿镜修复脊髓脊膜膨出的技术。在神经板上使用生物纤维素贴片引发新硬脑膜的形成,从而无需对胎儿硬脑膜进行初次修复,并且似乎能进一步改善神经发育结局。向羊膜腔内注入加湿二氧化碳需要适当的培训以及与经典“水下”胎儿镜检查所用设备不同的一套设备。为缩短新手团队的学习曲线,我们开发了一个结构化培训课程,包括三个关键步骤:(1)参观监考中心,(2)选择首例病例,以及(3)对外科团队进行现场培训。到达现场后,将进行:(1)对所有参与胎儿护理的专家进行理论讲座,(2)模拟培训,以及(3)手术监考。如果当地团队无法完成手术,监考团队可以接手。该培训课程已在五个不同国家成功使用:以色列、智利、意大利、美国和英国,并且所有当地团队都已独立开展手术,没有出现任何失败情况或产妇发病情况。由于候选病例数量少,以及良好结局与手术病例数量的直接关系,在胎儿医学中教授新手术具有挑战性。其他想要开展这类新型微创治疗的团队可以采用本提议的培训模块。