Thomas Jefferson University Hospital, Department of Radiology, 132 S 10th St., Philadelphia, PA 19017, USA.
Thomas Jefferson University Hospital, Department of Radiology, 132 S 10th St., Philadelphia, PA 19017, USA.
Clin Imaging. 2021 Sep;77:180-186. doi: 10.1016/j.clinimag.2021.03.030. Epub 2021 Mar 29.
Fibrotic lung changes are well-known complications of SARS, MERS, and ARDS from other causes and are anticipated in recovered COVID patients. However, there is limited data so far showing a temporal relationship between lung changes on imaging in the acute phase and follow-up imaging after recovery from the infection. We present 12 patients who demonstrate the development of interstitial lung changes and pulmonary fibrosis in the same distribution and pattern as the acute phase findings, up to 6 months after the acute infection, demonstrating a direct relationship between these changes and COVID-19 pneumonia.
纤维化肺部改变是 SARS、MERS 和其他原因引起的 ARDS 的已知并发症，在康复的 COVID 患者中也可预期。然而，目前有限的数据显示，在感染恢复后的急性阶段和随访成像之间，肺部影像学改变之间存在时间关系。我们介绍了 12 例患者，他们在急性感染后长达 6 个月的时间内，在相同的分布和模式下出现了间质性肺改变和肺纤维化，这表明这些改变与 COVID-19 肺炎之间存在直接关系。
