COVID-19 大流行对头颈部癌症幸存者生活质量的影响。
The impact of the COVID-19 pandemic on the quality of life of head and neck cancer survivors.
机构信息
Department of Otorhinolaryngology, Careggi University Hospital, Largo Brambilla 3, 50134, Florence, Italy.
Department of Otorhinolaryngology, Azienda Ospedaliera Universitaria Senese, Siena, Italy.
出版信息
Support Care Cancer. 2021 Nov;29(11):6297-6304. doi: 10.1007/s00520-021-06198-6. Epub 2021 Apr 15.
BACKGROUND
Head and neck cancer (HNC) survivors are particularly vulnerable to the deleterious consequences of lockdown and social distancing. The psychosocial effects of the COVID-19 pandemic on this group are still unknown, and we want to explore how their quality of life (QoL) has changed in this unique situation.
MATERIALS AND METHODS
An online survey, composed of pandemic-specific items, plus the EORTC QLQ-C30, was administered to a cohort of HNC survivors. Using previously published reference values as a control group, we have evaluated the impact of the pandemic on their QoL. We have also explored the differences between those who had received a total laryngectomy (LP, laryngectomized population) vs other HNC patients, in order to assess the role of tracheostomy in this regard.
RESULTS
One hundred and twenty-one HNC patients completed the survey. The scores of the physical (80.5 vs 85, p = 0.028), role (78 vs 84, p = 0.030), and emotional functioning (76 vs 81, p = 0.041) were significantly different in the two groups, with worse functioning in our patients. Comparing LP with the other HNC patients, social (76.6 vs 88.9, p = 0.008) and physical functioning (75.5 vs 86.1, p = 0.006) were significantly worse in the former group. LP also reported a greater perception that others are afraid to be close to them (1.67 vs 1.32, p = 0.020). No differences were found between LP with and without voice prosthesis.
CONCLUSIONS
Our results show how HNC patients are at high risk for a worsening in QoL because of the ongoing COVID-19 global pandemic.
背景
头颈部癌症（HNC）幸存者特别容易受到封锁和社交隔离的有害影响。COVID-19 大流行对这一群体的心理社会影响尚不清楚，我们想探讨他们在这种特殊情况下的生活质量（QoL）发生了怎样的变化。
材料与方法
一项在线调查，由特定于大流行的项目和 EORTC QLQ-C30 组成，被用于一组 HNC 幸存者。我们使用之前发表的参考值作为对照组，评估了大流行对他们 QoL 的影响。我们还比较了接受全喉切除术（LP，喉切除人群）与其他 HNC 患者之间的差异，以评估气管造口术在这方面的作用。
结果
121 名 HNC 患者完成了调查。两组的身体（80.5 对 85，p = 0.028）、角色（78 对 84，p = 0.030）和情绪功能（76 对 81，p = 0.041）评分存在显著差异，喉切除术患者的功能更差。与其他 HNC 患者相比，LP 患者的社会（76.6 对 88.9，p = 0.008）和身体功能（75.5 对 86.1，p = 0.006）明显更差。LP 患者也报告说，他们感觉别人更害怕接近他们（1.67 对 1.32，p = 0.020）。使用和不使用语音假体的 LP 患者之间没有差异。
结论
我们的研究结果表明，由于持续的 COVID-19 全球大流行，HNC 患者的 QoL 风险很高。
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