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撤稿:巨噬细胞来源的外泌体中的 microRNA-21-5p 下调通过抑制金属蛋白酶组织抑制剂 3 抑制心肌梗死后心室重构。

RETRACTED: Downregulation of microRNA-21-5p from macrophages-derived exosomes represses ventricular remodeling after myocardial infarction via inhibiting tissue inhibitors of metalloproteinase 3.

机构信息

Cardiovascular Department, The Second Affiliated Hospital of Zhengzhou University, Zhengzhou 450014, Henan, China.

Cardiovascular Department, The Second Affiliated Hospital of Zhengzhou University, Zhengzhou 450014, Henan, China.

出版信息

Int Immunopharmacol. 2021 Jul;96:107611. doi: 10.1016/j.intimp.2021.107611. Epub 2021 Apr 18.

Abstract

This article has been retracted: please see Elsevier Policy on Article Withdrawal (http://www.elsevier.com/locate/withdrawalpolicy). This article has been retracted at the request of the Editor-in-Chief. Concern was raised about the reliability of the Western blot results in Figs. 1E, 5B and 6B, which appear to have the same eyebrow shaped phenotype as many other publications tabulated here (https://docs.google.com/spreadsheets/d/149EjFXVxpwkBXYJOnOHb6RhAqT4a2llhj9LM60MBffM/edit#gid=0 [docs.google.com]). The journal requested the corresponding author comment on these concerns and provide the raw data. However, the authors were not responsive to the request for comment. Since original data could not be provided, the overall validity of the results could not be confirmed. Therefore, the Editor-in-Chief decided to retract the article.

摘要

本文已被撤回

请参阅爱思唯尔关于文章撤回的政策(http://www.elsevier.com/locate/withdrawalpolicy)。应主编要求,本文已被撤回。人们对图 1E、5B 和 6B 中的 Western blot 结果的可靠性提出了质疑,这些结果似乎与这里列出的许多其他出版物(https://docs.google.com/spreadsheets/d/149EjFXVxpwkBXYJOnOHb6RhAqT4a2llhj9LM60MBffM/edit#gid=0 [docs.google.com])具有相同的眉形表型。期刊要求通讯作者对这些问题发表评论并提供原始数据。然而,作者没有回应评论请求。由于无法提供原始数据,因此无法确认结果的整体有效性。因此,主编决定撤回该文章。

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