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电话传递教育和行为技能干预对非裔美国糖尿病成人的成本效益。

Cost-effectiveness of Telephone-Delivered Education and Behavioral Skills Intervention for African American Adults with Diabetes.

机构信息

Division of General Internal Medicine, Department of Medicine, Medical College of Wisconsin, Milwaukee, WI.

Center for Advancing Population Science, Medical College of Wisconsin, Milwaukee, WI.

出版信息

Ethn Dis. 2021 Apr 15;31(2):217-226. doi: 10.18865/ed.31.2.217. eCollection 2021 Spring.

Abstract

PURPOSE

Evaluate cost-effectiveness of a telephone-delivered education and behavioral skills intervention in reducing glycemic control (HbA1c) and decreasing risk of complications.

METHODS

Data from a randomized controlled trial, conducted from August 1, 2008 - June 30, 2010 and using a 2x2 factorial design delivered to 255 African American adults not meeting glycemic targets for diabetes were used. Though the primary aim found no significant differences in HbA1c between groups, there was an overall drop in HbA1c across arms and differential cost. Primary clinical outcome was HbA1c measured at 12-months. Costs were estimated based on self-reported utilization of primary care, emergency, and other health care. Costs due to lost wages were calculated based on self-reported days of work missed due to illness. The Michigan Model for Diabetes was used to estimate 10-year probability of developing congestive heart failure, cardiovascular disease, end stage renal disease, stroke, myocardial infarction, all cause death, and CVD death. Total cost per patient and clinical outcomes were used to estimate an incremental cost effectiveness ratio (ICER) using non-parametric bootstrapping.

RESULTS

ICERs indicated combined education and skills intervention was $3,630 less expensive than usual care to achieve a 0.6% decrease in HbA1c and was between $34,000 and $95,000 less expensive than usual care to reduce risk of complications. The knowledge only intervention was $661 less expensive than usual care and the behavioral skills only intervention did not indicate cost effectiveness.

CONCLUSION

The combined intervention ICER for HbA1c is comparable to other education programs and the ICER to reduce the probability of complications falls below previously recommended long-term cut-off of $100,000, suggesting cost-effectiveness in an African American population.

摘要

目的

评估电话传递教育和行为技能干预在降低血糖控制(HbA1c)和减少并发症风险方面的成本效益。

方法

使用 2008 年 8 月 1 日至 2010 年 6 月 30 日进行的一项随机对照试验的数据,采用 2x2 析因设计,对 255 名不符合糖尿病血糖目标的非裔美国成年人进行干预。尽管主要目标发现组间 HbA1c 无显著差异,但各臂的 HbA1c 总体下降,且成本存在差异。主要临床结局为 12 个月时测量的 HbA1c。根据自我报告的初级保健、急诊和其他医疗保健的利用情况来估计成本。根据因疾病而错过的工作日数,计算因旷工而导致的工资损失成本。使用密歇根州糖尿病模型来估计 10 年内发生充血性心力衰竭、心血管疾病、终末期肾病、中风、心肌梗死、全因死亡和心血管疾病死亡的概率。使用非参数自举法,根据每位患者的总成本和临床结局,估算增量成本效益比(ICER)。

结果

ICER 表明,与常规护理相比,综合教育和技能干预可节省 3630 美元,实现 HbA1c 降低 0.6%,并且与常规护理相比,可降低并发症风险 34000 美元至 95000 美元。仅知识干预比常规护理便宜 661 美元,而仅行为技能干预并不经济。

结论

HbA1c 的联合干预 ICER 与其他教育计划相当,降低并发症概率的 ICER 低于先前推荐的 10 万美元长期截止值,表明在非裔美国人中具有成本效益。

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