Li Rongrong, Tang Hao, Xu Huaming, Ren Yingli, Li Shujin, Shen Jilu
Department of Clinical Laboratory, Hefei Hospital Affiliated to Anhui Medical University the Second People's Hospital of Hefei City, Hefei, Anhui Province, People's Republic of China.
The Fourth Affiliated Hospital of Anhui Medical University Laboratory, Hefei, People's Republic of China.
Infect Drug Resist. 2021 Apr 14;14:1423-1425. doi: 10.2147/IDR.S303187. eCollection 2021.
Direct-on-target microdroplet growth assay is a new technique for analysing bacterial sensitivity and mechanisms of resistance. It is based on matrix-assisted laser desorption/ionization time-of-flight mass spectrometry and allows for easy and rapid testing. Here, we describe the development and procedure of the direct-on-target microdroplet growth assay and summarise the latest clinical applications.
直接靶向微滴生长测定法是一种用于分析细菌敏感性和耐药机制的新技术。它基于基质辅助激光解吸/电离飞行时间质谱,能够实现简便快速的检测。在此,我们描述了直接靶向微滴生长测定法的开发和操作流程,并总结了其最新临床应用情况。