α干扰素（IFNα）对多种人肿瘤异种移植瘤的作用。
Effect of interferon-alpha (IFN alpha) on various human tumor xenografts.
作者信息
Nagy P, Kopper L, Gyapay G, Péterfy F, Lapis K
机构信息
1st Institute of Pathology and Experimental Cancer Research, Semmelweis Medical University, Budapest, Hungary.
出版信息
Anticancer Res. 1988 May-Jun;8(3):467-9.
The growth of some human tumor xenografts (3 out of 8, melanoma, non-Hodgkin's lymphoma, squamous cell carcinoma) was successfully--but moderately and temporarily--inhibited, when interferon-alpha (EGIS, Hungary) was given for 10 days. The route of administration (intratumoral or intraperitoneal) was usually not a decisive factor. An attempt to potentiate IFNa action with Zymozan or Cyclophosphamide did not succeed.
当给予α干扰素（匈牙利EGIS公司生产）10天时，一些人肿瘤异种移植瘤（8个中有3个，即黑色素瘤、非霍奇金淋巴瘤、鳞状细胞癌）的生长成功受到抑制——但抑制程度为中等且呈暂时性。给药途径（瘤内或腹腔内）通常不是决定性因素。尝试用酵母多糖或环磷酰胺增强IFNa的作用未成功。
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