Suppr超能文献

口服姜黄素凝胶辅助龈下刮治和根面平整的抗牙菌斑和抗炎作用评估:一项临床研究

Evaluation of Anti-plaque and Anti-inflammatory Effects of Oral Curcumin Gel as Adjunct to Scaling and Root Planing: A Clinical Study.

作者信息

Pandey Vijayendra, Kumar Deepak, Nisha Swet, Gupta Alok Kumar, Verma Tanya, Kumari Ayusha

机构信息

Department of Periodontology, Vananchal Dental College and Hospital, Garhwa, Jharkhand, India.

Department of Periodontology, Haldia Institute of Dental Sciences and Research, Haldia, West Bengal, India.

出版信息

Int J Appl Basic Med Res. 2021 Apr-Jun;11(2):90-94. doi: 10.4103/ijabmr.IJABMR_391_19. Epub 2021 Apr 8.

Abstract

CONTEXT

The adverse effects associated with traditional adjunctive chemical agents in the management of gingivitis has stimulated research into search for alternate molecules including herbal products. Aims-To compare the effects of oral curcumin gel as an adjunct to scaling and root planing (SRP) with the effects achieved by SRP alone by assessing their effects on plaque, gingival inflammation and gingival bleeding.

MATERIALS AND METHODS

Sixty patients in the age group of 20-60 years were recruited employing inclusion and exclusion criteria. Study population was randomly divided into two groups. Group A-test group was instructed to use twice daily the experimental curcumin gel after initial SRP. Group B-control group received only SRP. Parameters recorded were plaque index (PI), gingival index (GI) and sulcus bleeding index (SBI) on day 0 (baseline), days 7, 14, and 21 along with subjective assessment of any reported untoward side effect. Data was analyzed statistically.

RESULTS

The PI, GI and SBI decreased in both the test group and control group from day 0 to day 21 consecutively. Intergroup comparison shows that all the parameters were statistically significant in Group A ( < 0.001) as compared to Group B.

CONCLUSION

Curcumin gel has significant antiplaque and anti-inflammatory effect in the treatment of gingivitis and can be effectively employed as an adjunct to SRP.

摘要

背景

传统辅助化学药物在牙龈炎治疗中产生的不良反应激发了对包括草药产品在内的替代分子的研究。目的:通过评估口服姜黄素凝胶作为龈下刮治术和根面平整术(SRP)辅助治疗手段与单纯SRP治疗手段对牙菌斑、牙龈炎症和牙龈出血的影响,对二者进行比较。

材料与方法

采用纳入和排除标准招募了60名年龄在20至60岁之间的患者。研究人群被随机分为两组。A组(试验组)在初次SRP后被要求每天使用两次实验性姜黄素凝胶。B组(对照组)仅接受SRP治疗。记录的参数包括第0天(基线)、第7天、第14天和第21天的菌斑指数(PI)、牙龈指数(GI)和龈沟出血指数(SBI),以及对任何报告的不良副作用的主观评估。对数据进行统计学分析。

结果

试验组和对照组的PI、GI和SBI从第0天到第21天均持续下降。组间比较显示,与B组相比,A组的所有参数均具有统计学意义(<0.001)。

结论

姜黄素凝胶在牙龈炎治疗中具有显著的抗菌斑和抗炎作用,可有效用作SRP的辅助治疗手段。

相似文献

本文引用的文献

5
Antibacterial Activity of Curcumin Against Periodontopathic Bacteria.姜黄素对牙周病原菌的抗菌活性
J Periodontol. 2016 Jan;87(1):83-90. doi: 10.1902/jop.2015.150260. Epub 2015 Oct 8.

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验