Li Junpeng, Hu Shuping, Jian Wei, Xie Chengjian, Yang Xingyong
College of Life Science, Chongqing Normal University, Chongqing, 401331, China.
Bot Stud. 2021 Apr 29;62(1):5. doi: 10.1186/s40529-021-00312-x.
Antimicrobial peptides (AMPs) are a class of short, usually positively charged polypeptides that exist in humans, animals, and plants. Considering the increasing number of drug-resistant pathogens, the antimicrobial activity of AMPs has attracted much attention. AMPs with broad-spectrum antimicrobial activity against many gram-positive bacteria, gram-negative bacteria, and fungi are an important defensive barrier against pathogens for many organisms. With continuing research, many other physiological functions of plant AMPs have been found in addition to their antimicrobial roles, such as regulating plant growth and development and treating many diseases with high efficacy. The potential applicability of plant AMPs in agricultural production, as food additives and disease treatments, has garnered much interest. This review focuses on the types of plant AMPs, their mechanisms of action, the parameters affecting the antimicrobial activities of AMPs, and their potential applications in agricultural production, the food industry, breeding industry, and medical field.
抗菌肽(AMPs)是一类短小的、通常带正电荷的多肽,存在于人类、动物和植物中。鉴于耐药病原体数量不断增加,抗菌肽的抗菌活性备受关注。对许多革兰氏阳性菌、革兰氏阴性菌和真菌具有广谱抗菌活性的抗菌肽是许多生物体抵御病原体的重要防御屏障。随着研究的不断深入,除了抗菌作用外,人们还发现了植物抗菌肽的许多其他生理功能,如调节植物生长发育以及高效治疗多种疾病。植物抗菌肽在农业生产、作为食品添加剂和疾病治疗方面的潜在适用性引起了广泛关注。本综述重点关注植物抗菌肽的类型、作用机制、影响抗菌肽抗菌活性的参数及其在农业生产、食品工业、育种行业和医学领域的潜在应用。