Department of Surgery, The University of Hong Kong Shenzhen Hospital, Shenzhen, Guangdong, People's Republic of China.
Head Neck. 2021 Aug;43(8):2523-2533. doi: 10.1002/hed.26733. Epub 2021 May 5.
This meta-analysis evaluates whether near-infrared autofluorescence (NIRAF) imaging reduces the risk of hypocalcemia after total thyroidectomy. A systematic literature search in PubMed, EMBASE, Web of Science, and Cochrane Library for studies from June 2011 to January 2021 comparing total thyroidectomy with NIRAF and conventional surgery (naked eye). Six eligible studies involving 2180 patients were included. The prevalence of transient hypocalcemia was 8.11% (40/493) and 25.19% (425/1687) in the NIRAF and naked eye groups (p < 0.0001), respectively. The prevalence of permanent hypocalcemia was 0% (0/493) and 2.19% (37/1687) in the NIRAF and naked eye groups (p = 0.05), respectively. NIRAF reduces the risk of transient hypocalcemia and may possibly lower the rate of permanent hypocalcemia. Nonetheless, further studies are needed to verify our results and evaluate the cost-effectiveness of NIRAF in real-world clinical practice.
这项荟萃分析评估了近红外自发荧光（NIRAF）成像是否降低了全甲状腺切除术患者低钙血症的风险。我们在 PubMed、EMBASE、Web of Science 和 Cochrane Library 中进行了系统的文献检索，以评估 2011 年 6 月至 2021 年 1 月期间的研究，这些研究比较了 NIRAF 和传统手术（肉眼）在全甲状腺切除术中的应用。纳入了 6 项符合条件的研究，涉及 2180 例患者。NIRAF 组和肉眼组的短暂性低钙血症发生率分别为 8.11%（40/493）和 25.19%（425/1687）（p<0.0001）。NIRAF 组和肉眼组的永久性低钙血症发生率分别为 0%（0/493）和 2.19%（37/1687）（p=0.05）。NIRAF 降低了短暂性低钙血症的风险，并且可能降低永久性低钙血症的发生率。然而，仍需要进一步的研究来验证我们的结果，并评估 NIRAF 在真实临床实践中的成本效益。
