Department of Cardiology, Hiroshima Red Cross Hospital and Atomic-bomb Survivors Hospital, Hiroshima, Japan.
Medicine (Baltimore). 2021 May 7;100(18):e25775. doi: 10.1097/MD.0000000000025775.
The relationship between spontaneous coronary artery dissection (SCAD) and takotsubo syndrome (TTS) remains unclear. Coexistence of SCAD and TTS has been reported in the literature. However, the relationship between these two diseases has not yet been elucidated.
A 36-year-old breastfeeding woman was brought to our hospital 52 days after cesarean section because of discomfort in her left arm and convulsions.
She was diagnosed of acute myocardial infarction (AMI). The convulsions were attributed to lethal arrhythmia.
An immediate coronary angiography revealed that her left anterior descending artery (LAD) was Type 2a SCAD, but with no flow limitation. In addition, a 12-lead electrocardiogram (ECG) revealed improvement in ST-elevation. We chose the conservative treatment according to the patient's needs.
Conservative treatment was unsuccessful. She developed another acute myocardial infarction requiring another percutaneous coronary intervention (PCI) during hospitalization. From the course of hospitalization, we suspected the coexistence of SCAD and TTS.
When we treat patients with SCAD, we should consider the possibility of coexistence of TTS and confirm left ventricular wall motion. Patients with SCAD may require invasive treatment, hence, should be monitored for a while. An urgent strategy for managing patients with SCAD who require PCI should be established.
自发性冠状动脉夹层(SCAD)与心尖球形综合征(TTS)之间的关系尚不清楚。文献中已有 SCAD 和 TTS 共存的报道。然而,这两种疾病之间的关系尚未阐明。
一位 36 岁的哺乳期妇女在剖宫产术后 52 天因左臂不适和抽搐被送往我院。
她被诊断为急性心肌梗死(AMI)。抽搐归因于致命性心律失常。
立即进行冠状动脉造影显示其左前降支(LAD)为 2a 型 SCAD,但无血流受限。此外,12 导联心电图(ECG)显示 ST 段抬高改善。根据患者的需求,我们选择了保守治疗。
保守治疗无效。她在住院期间又发生了另一次急性心肌梗死,需要再次行经皮冠状动脉介入治疗(PCI)。从住院期间的病情发展来看,我们怀疑同时存在 SCAD 和 TTS。
当我们治疗 SCAD 患者时,我们应该考虑到 TTS 共存的可能性,并确认左心室壁运动情况。SCAD 患者可能需要侵入性治疗,因此需要监测一段时间。应制定 SCAD 患者需要 PCI 的紧急治疗策略。