Department of Paediatrics and Neonatology, Nagoya City University Graduate School of Medical Sciences, Kawasumi 1, Mizuho-cho, Mizuho-ku, Nagoya, Japan.
Department of Paediatrics, Daido Hospital, Nagoya, Japan.
Sci Rep. 2021 May 5;11(1):9537. doi: 10.1038/s41598-021-88787-3.
Inappropriate preparation of respiratory gases is associated with serious complications during mechanical ventilation. To develop a temperature monitoring system of respiratory gases within the endotracheal tube, four newborn piglets were studied using an ultra-rapid-response thermometer attached to the closed endotracheal tube suction system. Respiratory gas temperatures were monitored at the mouth-corner level of the endotracheal tube using three thermocouples (T, inserted into the endotracheal tube via the closed suction system; T and T, embedded within the endotracheal tube 0.5 mm and 1.6 mm from the tube wall, respectively). Univariate analysis showed that inspiratory T and inspiratory T were positively correlated with inspiratory T (both p < 0.001). Multivariate analysis showed the dependence of inspiratory T on inspiratory T and T and deflation of endotracheal tube cuff (p < 0.001, p = 0.001 and p = 0.046, respectively). Inspiratory gas temperature within the endotracheal tube can be monitored using a thermometer attached to the closed endotracheal tube suction system. Our system, with further validation, might help optimise respiratory gas humidification during mechanical ventilation.
不适当的呼吸气体准备与机械通气期间的严重并发症有关。为了在气管内管内开发呼吸气体的温度监测系统,使用附接到封闭气管内管抽吸系统的超快速响应温度计研究了四个新生小猪。使用三个热电偶(T,通过封闭的抽吸系统插入气管内管; T和T,分别嵌入气管内管中距管壁 0.5毫米和 1.6毫米处)在气管内管的角水平监测呼吸气体温度。单变量分析表明,吸气 T 和吸气 T 与吸气 T 呈正相关(均 p <0.001)。多变量分析表明,吸气 T 依赖于吸气 T 和 T 以及气管内管套囊的放气(p <0.001,p = 0.001 和 p = 0.046,分别)。可以使用附接到封闭气管内管抽吸系统的温度计监测气管内管内的吸气气体温度。我们的系统,经过进一步验证,可能有助于优化机械通气期间呼吸气体加湿。