University of Pennsylvania, 418 Curie Blvd, Room 222L, Philadelphia, PA, 19104, USA.
University of Pennsylvania, 418 Curie Blvd, Room 235L, Philadelphia, PA, 19104, USA.
Curr HIV/AIDS Rep. 2021 Aug;18(4):339-350. doi: 10.1007/s11904-021-00557-y. Epub 2021 May 6.
Linkage to and retention in HIV care, as conceptualized in the HIV care continuum, remain critical steps towards achieving and maintaining viral suppression. We evaluated recently published (Jan 2018-Nov 2020) peer-reviewed clinical trials of linkage to and retention in care outcomes in the United States.
We identified 12 trials evaluating linkage to and retention in care outcomes in the United States. Most trials did not adhere to standardized definitions or metrics for linkage to or retention in HIV care, hindering comparisons between studies. Four interventions indicated improvements on linkage to or retention in HIV care at follow-up, relying on behavioral incentives and/or case management as key intervention strategies. We recommend the adoption standardize metrics across linkage and retention trials, and the future use of implementation science frameworks to identify implementation facilitators and barriers, and evaluate key strategies associated with improvements in linkage to and retention in care.
艾滋病护理连续体概念中的艾滋病病毒(HIV)护理的衔接和维持仍然是实现和维持病毒抑制的关键步骤。我们评估了最近发表的(2018 年 1 月至 2020 年 11 月)关于美国艾滋病病毒护理衔接和维持护理结果的同行评议临床试验。
我们确定了 12 项评估美国艾滋病病毒护理衔接和维持护理结果的临床试验。大多数试验没有遵守艾滋病病毒护理衔接或维持的标准化定义或指标,这阻碍了研究之间的比较。四项干预措施表明在后续随访中在艾滋病病毒护理的衔接或维持方面有所改善,这依赖于行为激励和/或个案管理作为关键的干预策略。我们建议在衔接和维持试验中采用标准化指标,并在未来使用实施科学框架来确定实施的促进因素和障碍,以及评估与改善衔接和维持护理相关的关键策略。