伴有前房积血的顽固性角膜炎
Recalcitrant Keratitis with Hyphaema.
作者信息
Chan Amy, Oo Hnin Hnin, Stanley Philip, Chang Benjamin
机构信息
Department of Ophthalmology and Visual Sciences, Khoo Teck Puat Hospital, Singapore, Singapore.
出版信息
Case Rep Ophthalmol. 2021 Apr 12;12(1):214-218. doi: 10.1159/000512473. eCollection 2021 Jan-Apr.
PURPOSE
To report a case of recalcitrant pseudomonas keratitis with a rare presentation of hyphaema.
OBSERVATION
A 45-year-old female was noted to have contact lens-related pseudomonas keratitis with hyphaema. The organism was refractory to multiple antibiotics and only responded to Tazocin eye drops.
CONCLUSION AND IMPORTANCE
Hyphaema is a rare presentation in bacterial keratitis and could represent infection with an especially virulent organism. Use of Aspirin could precipitate hyphaema in infective keratitis. Alternative antibiotic choices such as Tazocin, colistin, meropenem, and imipenem can be considered when standard therapy is ineffective for multidrug-resistant Pseudomonas keratitis.
目的
报告一例难治性铜绿假单胞菌角膜炎伴罕见前房积血表现的病例。
观察
一名45岁女性被诊断为与隐形眼镜相关的铜绿假单胞菌角膜炎伴前房积血。该病原体对多种抗生素耐药，仅对他唑仙眼药水有反应。
结论与重要性
前房积血在细菌性角膜炎中是一种罕见表现，可能代表感染了特别具有毒力的病原体。使用阿司匹林可能会在感染性角膜炎中引发前房积血。当标准治疗对多重耐药的铜绿假单胞菌角膜炎无效时，可以考虑使用替代抗生素，如他唑仙、多粘菌素、美罗培南和亚胺培南。
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