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用于操纵超顺磁性微珠的贝塞尔光束光镊

Bessel beam optical tweezers for manipulating superparamagnetic beads.

作者信息

Andrade U M S, Garcia A M, Rocha M S

出版信息

Appl Opt. 2021 Apr 20;60(12):3422-3429. doi: 10.1364/AO.420600.

Abstract

We propose a Bessel beam optical tweezers setup that can stably trap superparamagnetic beads. The trap stiffness measured is practically independent of the radius of the Bessel beam and of the bead height (distance from the coverlip of the sample chamber), indicating that the beads can be trapped with high accuracy within a wide range of such parameters. On the other hand, the trap stiffness exhibits the expected linear increase with the laser power, despite the non-negligible absorption coefficient of the superparamagnetic beads. A geometrical optics model that considers spherical aberration and light absorption by the beads was used to predict the optical forces and trap stiffness, showing excellent agreement with the experimental data. We believe the results presented here advance the field of optical trapping manipulation of absorbing magnetic particles, and future applications will involve, for example, the design of new hybrid optomagnetic tweezers.

摘要

我们提出了一种能够稳定捕获超顺磁性微珠的贝塞尔光束光镊装置。所测量的捕获刚度实际上与贝塞尔光束的半径以及微珠高度(距样品腔盖玻片的距离)无关,这表明在如此广泛的参数范围内,微珠能够以高精度被捕获。另一方面,尽管超顺磁性微珠的吸收系数不可忽略,但捕获刚度随激光功率呈现出预期的线性增加。一个考虑了球差和微珠光吸收的几何光学模型被用于预测光力和捕获刚度,结果与实验数据显示出极好的一致性。我们相信此处展示的结果推动了吸收性磁性粒子的光镊操纵领域的发展,并且未来的应用将包括,例如,新型混合光磁镊的设计。

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