腹部成像中空间相干性与原位压力的关系。
On the Relationship between Spatial Coherence and In Situ Pressure for Abdominal Imaging.
机构信息
Department of Biomedical Engineering, Duke University, Durham, North Carolina, USA.
Joint Department of Biomedical Engineering, University of North Carolina at Chapel Hill and North Carolina State University, Chapel Hill, North Carolina, USA.
出版信息
Ultrasound Med Biol. 2021 Aug;47(8):2310-2320. doi: 10.1016/j.ultrasmedbio.2021.03.008. Epub 2021 May 11.
Tissue harmonic signal quality has been shown to improve with elevated acoustic pressure. The peak rarefaction pressure (PRP) for a given transmit, however, is limited by the Food and Drug Administration guidelines for mechanical index. We have previously demonstrated that the mechanical index overestimates in situ PRP for tightly focused beams in vivo, due primarily to phase aberration. In this study, we evaluate two spatial coherence-based image quality metrics-short-lag spatial coherence and harmonic short-lag spatial coherence-as proxy estimates for phase aberration and assess their correlation with in situ PRP in simulations and experiments when imaging through abdominal body walls. We demonstrate strong correlation between both spatial coherence-based metrics and in situ PRP (R = 0.77 for harmonic short-lag spatial coherence, R = 0.67 for short-lag spatial coherence), an observation that could be leveraged in the future for patient-specific selection of acoustic output.
组织谐波信号质量已被证明随着声压的升高而提高。然而，给定发射的峰值稀疏压力 (PRP) 受到食品和药物管理局机械指数指南的限制。我们之前已经证明，由于相位像差，机械指数高估了体内紧密聚焦光束的实际 PRP。在这项研究中，我们评估了两种基于空间相干性的图像质量指标——短延迟空间相干性和谐波短延迟空间相干性——作为相位像差的代理估计，并在通过腹部体壁成像时评估了它们与实际 PRP 的相关性。我们证明了这两种基于空间相干性的指标与实际 PRP 之间存在很强的相关性（谐波短延迟空间相干性的 R 值为 0.77，短延迟空间相干性的 R 值为 0.67），这一观察结果将来可以用于针对患者的声输出选择。
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