Suppr超能文献

精子DNA碎片化:临床实践指南的批判性评估

Sperm DNA Fragmentation: A Critical Assessment of Clinical Practice Guidelines.

作者信息

Agarwal Ashok, Farkouh Ala'a, Parekh Neel, Zini Armand, Arafa Mohamed, Kandil Hussein, Tadros Nick, Busetto Gian Maria, Ambar Rafael, Parekattil Sijo, Boitrelle Florence, Sallam Hassan, Jindal Sunil, Ko Edmund, Simopoulou Mara, Park Hyun Jun, Sadighi Mohammad Ali, Saleh Ramadan, Ramsay Jonathan, Martinez Marlon, Elbardisi Haitham, Alvarez Juan, Colpi Giovanni, Gosalvez Jaime, Evenson Donald, Shah Rupin

机构信息

American Center for Reproductive Medicine, Cleveland Clinic, Cleveland, OH, USA.

Department of Urology, Cleveland Clinic, Cleveland, OH, USA.

出版信息

World J Mens Health. 2022 Jan;40(1):30-37. doi: 10.5534/wjmh.210056. Epub 2021 Apr 21.

Abstract

Sperm DNA fragmentation (SDF) is implicated in male infertility and adverse reproductive outcomes. With the publication of many studies regarding the etiologies and contributors to SDF, as well as the effects of SDF, guidelines are necessary to aid clinicians in the application of SDF for male fertility evaluation. Two recent clinical practice guidelines were published by Agarwal et al and Esteves et al. In this article, we have evaluated and compared both guidelines. We have found fairly similar recommendations between the two guidelines and have also highlighted the differences between them. Finally, we have summarized and combined the best practice recommendations from both guidelines.

摘要

精子DNA碎片化(SDF)与男性不育和不良生殖结局有关。随着许多关于SDF病因、影响因素以及SDF作用的研究发表,有必要制定指南以帮助临床医生在男性生育力评估中应用SDF。Agarwal等人和Esteves等人最近发表了两项临床实践指南。在本文中,我们对这两项指南进行了评估和比较。我们发现这两项指南之间的建议相当相似,同时也突出了它们之间的差异。最后,我们总结并整合了两项指南中的最佳实践建议。

相似文献

1
Sperm DNA Fragmentation: A Critical Assessment of Clinical Practice Guidelines.
World J Mens Health. 2022 Jan;40(1):30-37. doi: 10.5534/wjmh.210056. Epub 2021 Apr 21.
2
Sperm DNA Fragmentation: A New Guideline for Clinicians.
World J Mens Health. 2020 Oct;38(4):412-471. doi: 10.5534/wjmh.200128. Epub 2020 Aug 6.
3
Sperm DNA damage and its impact on male reproductive health: a critical review for clinicians, reproductive professionals and researchers.
Expert Rev Mol Diagn. 2019 Jun;19(6):443-457. doi: 10.1080/14737159.2019.1614916. Epub 2019 May 13.
8
Clinical utility of sperm DNA fragmentation testing: practice recommendations based on clinical scenarios.
Transl Androl Urol. 2016 Dec;5(6):935-950. doi: 10.21037/tau.2016.10.03.
10
An update on clinical and surgical interventions to reduce sperm DNA fragmentation in infertile men.
Andrology. 2020 Jan;8(1):53-81. doi: 10.1111/andr.12724. Epub 2019 Dec 9.

引用本文的文献

1
The Chromatin Configuration Promotes Constitutional Chromosomal Rearrangements in Post-Meiotic Sperm.
Methods Mol Biol. 2025;2968:549-556. doi: 10.1007/978-1-0716-4750-9_33.
4
Influence of Body Mass Index (BMI) and Waist-Hip Ratio (WHR) on Selected Semen Parameters.
Int J Mol Sci. 2025 Apr 25;26(9):4089. doi: 10.3390/ijms26094089.
5
Optimizing Assisted Reproductive Techniques: The Role of L-Carnitine, Acetyl-L-Carnitine, and IMSI in Managing High-Sperm DNA Fragmentation.
J Pharm Bioallied Sci. 2024 Dec;16(Suppl 4):S4037-S4040. doi: 10.4103/jpbs.jpbs_1410_24. Epub 2024 Dec 5.
6
Association of abstinence time with semen quality in men who undergoing fertility evaluation: a cross-sectional study from 3052 participants.
Front Endocrinol (Lausanne). 2025 Jan 24;16:1472333. doi: 10.3389/fendo.2025.1472333. eCollection 2025.
8
Septins as key players in spermatogenesis, fertilisation and pre-implantation embryogenic cytoplasmic dynamics.
Cell Commun Signal. 2024 Oct 28;22(1):523. doi: 10.1186/s12964-024-01889-z.
10
Bacteriospermia-Related Male Infertility: A Case Report on Diagnostic and Therapeutic Approaches.
Cureus. 2024 Jun 23;16(6):e62973. doi: 10.7759/cureus.62973. eCollection 2024 Jun.

本文引用的文献

2
Efficacy of varicocelectomy for sperm DNA integrity improvement: A meta-analysis.
Andrologia. 2021 Feb;53(1):e13885. doi: 10.1111/and.13885. Epub 2020 Oct 28.
3
Sperm DNA fragmentation testing: Summary evidence and clinical practice recommendations.
Andrologia. 2021 Mar;53(2):e13874. doi: 10.1111/and.13874. Epub 2020 Oct 27.
4
Sperm DNA Fragmentation: A New Guideline for Clinicians.
World J Mens Health. 2020 Oct;38(4):412-471. doi: 10.5534/wjmh.200128. Epub 2020 Aug 6.
5
The Use of Testicular Sperm for Intracytoplasmic Sperm Injection in Patients with High Sperm DNA Damage: A Systematic Review.
World J Mens Health. 2021 Jul;39(3):391-398. doi: 10.5534/wjmh.200084. Epub 2020 Jun 25.
6
Comparative analysis of tests used to assess sperm chromatin integrity and DNA fragmentation.
Andrologia. 2021 Mar;53(2):e13718. doi: 10.1111/and.13718. Epub 2020 Jul 6.
7
Etiologies of sperm DNA damage and its impact on male infertility.
Andrologia. 2021 Feb;53(1):e13706. doi: 10.1111/and.13706. Epub 2020 Jun 19.
8
Seminal oxidation-reduction potential and sperm DNA fragmentation index increase among infertile men with varicocele.
Hum Fertil (Camb). 2022 Feb;25(1):142-146. doi: 10.1080/14647273.2020.1712747. Epub 2020 Jan 20.
9
ESHRE guideline: recurrent pregnancy loss.
Hum Reprod Open. 2018 Apr 6;2018(2):hoy004. doi: 10.1093/hropen/hoy004. eCollection 2018.
10
Sperm DNA Fragmentation: Mechanisms of Origin.
Adv Exp Med Biol. 2019;1166:75-85. doi: 10.1007/978-3-030-21664-1_5.

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验