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多米尼加共和国东部地区成年 HIV 感染者抗 HIV 治疗依从性的障碍。

Barriers to HIV treatment adherence among adults living with HIV in the eastern Dominican Republic.

机构信息

19994Bruce W Carter Department of Veterans Affairs Medical Center, Miami, FL, USA.

Clinica de Familia La Romana, La Romana, Dominican Republic.

出版信息

Int J STD AIDS. 2021 Oct;32(11):1014-1019. doi: 10.1177/09564624211014102. Epub 2021 May 14.

Abstract

Despite access to nationally supplied antiretroviral treatment, viral load suppression rates remain suboptimal in the Dominican Republic. Counseling and support services are available but mainly targeted to those identified as having the most need. At Clínica de Familia La Romana (CFLR) in La Romana, all patients undergo a structured baseline interview including exploration of expected barriers to care. We conducted a retrospective cohort study of a random sample of patients at CFLR with treatment initiation between 1 January 2015 and 1 December 2017 to determine if self-identified barriers to HIV care predict viral load suppression. Viral load suppression occurred in 63% of the 203 patients evaluated. Lack of food ( = 19) was significantly associated with lack of viral suppression (OR 3.0, 95% CI 1.14-7.87). Nondisclosure of HIV status ( = 24) showed evidence for a protective effect (OR 0.33; 95% CI 0.11-1.0). Further steps should be taken to address food insecurity as well as to understand associated barriers to care among individuals with food insecurity.

摘要

尽管可以获得国家供应的抗逆转录病毒治疗,但多米尼加共和国的病毒载量抑制率仍然不理想。咨询和支持服务是可用的,但主要针对那些被认为最需要的人。在拉罗马纳的拉罗马纳家庭诊所(CFLR),所有患者都接受了一项结构化的基线访谈,包括对预期护理障碍的探索。我们对 2015 年 1 月 1 日至 2017 年 12 月 1 日期间在 CFLR 开始治疗的随机患者样本进行了回顾性队列研究,以确定自我识别的 HIV 护理障碍是否预测病毒载量抑制。在评估的 203 名患者中,有 63%的患者病毒载量得到了抑制。缺乏食物( = 19)与缺乏病毒抑制显著相关(OR 3.0,95%CI 1.14-7.87)。未披露 HIV 状况( = 24)显示出保护作用的证据(OR 0.33;95%CI 0.11-1.0)。应采取进一步措施来解决粮食不安全问题,并了解粮食不安全人群中与护理相关的障碍。

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