儿童重症新型冠状病毒肺炎的固有细胞反应：CD64、CD18和CD11a的表达分析 - Suppr

Innate cell response in severe SARS-CoV-2 infection in children: Expression analysis of CD64, CD18 and CD11a.

作者信息

García-Salido A, García-Teresa M Á, Leoz-Gordillo I, Martínez de Azagra-Garde A, Cabrero-Hernández M, Ramirez-Orellana M

机构信息

Pediatric Critical Care Unit, Hospital Infantil Universitario Niño Jesús, Madrid, Spain.

Pediatric Oncohematology Unit, Flow Cytometry Laboratory, Hospital Infantil Universitario Niño Jesús, Madrid, Spain.

出版信息

Med Intensiva. 2022 Jan;46(1):50-53. doi: 10.1016/j.medin.2020.09.003. Epub 2020 Sep 30.

DOI:10.1016/j.medin.2020.09.003

PMID:33994613

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7524662/

Abstract

摘要

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Innate cell response in severe SARS-CoV-2 infection in children: Expression analysis of CD64, CD18 and CD11a.儿童重症新型冠状病毒肺炎的固有细胞反应：CD64、CD18和CD11a的表达分析

Med Intensiva. 2022 Jan;46(1):50-53. doi: 10.1016/j.medin.2020.09.003. Epub 2020 Sep 30.

Innate cell response in severe SARS-CoV-2 infection in children: Expression analysis of CD64, CD18 and CD11a.儿童严重新型冠状病毒肺炎感染中的固有细胞反应：CD64、CD18和CD11a的表达分析

Med Intensiva (Engl Ed). 2022 Jan;46(1):50-53. doi: 10.1016/j.medine.2020.09.008.

CD64, CD11a and CD18 leukocytes expression in children with SARS-CoV-2 multisystem inflammatory syndrome versus children with Kawasaki disease: Similar but not the same.与川崎病患儿相比，新型冠状病毒2型多系统炎症综合征患儿的CD64、CD11a和CD18白细胞表达：相似但不同。

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Med Clin (Barc). 2021 Jan 22;156(2):89-91. doi: 10.1016/j.medcli.2020.09.002. Epub 2020 Sep 25.

Flow cytometry analysis of CD64, CD18, CD11a and CD11b in four children with Bordetella pertussis infection and admitted to critical care: New biomarkers?对4名感染百日咳博德特氏菌并入住重症监护病房的儿童进行CD64、CD18、CD11a和CD11b的流式细胞术分析：新的生物标志物？

Med Intensiva (Engl Ed). 2019 Oct;43(7):446-449. doi: 10.1016/j.medin.2017.10.007. Epub 2017 Dec 26.

Aggravated Lyme carditis in CD11a-/- and CD11c-/- mice.CD11a基因敲除小鼠和CD11c基因敲除小鼠中加重的莱姆病心肌炎

Infect Immun. 2005 Nov;73(11):7637-43. doi: 10.1128/IAI.73.11.7637-7643.2005.

[intercellular adhesion molecule-1 and CD11a/CD18 expression in coronary heart disease].[细胞间黏附分子-1及CD11a/CD18在冠心病中的表达]

Zhejiang Da Xue Xue Bao Yi Xue Ban. 2002 Jun;31(3):193-194. doi: 10.3785/j.issn.1008-9292.2002.03.015.

Expression of retroviral transduced human CD18 in murine cells: an in vitro model of gene therapy for leukocyte adhesion deficiency.逆转录病毒转导的人CD18在鼠细胞中的表达：白细胞黏附缺陷基因治疗的体外模型

Hum Gene Ther. 1991 Fall;2(3):221-8. doi: 10.1089/hum.1991.2.3-221.

Analysis of the role of leukocyte function-associated antigen-1 in activation of human influenza virus-specific T cell clones.白细胞功能相关抗原-1在人流感病毒特异性T细胞克隆激活中的作用分析

J Immunol. 1990 May 1;144(9):3281-7.

CD11a/CD18 (LFA-1) integrin engagement enhances biosynthesis of early cytokines by activated T cells.CD11a/CD18（淋巴细胞功能相关抗原-1）整合素的结合可增强活化T细胞早期细胞因子的生物合成。

Cell Immunol. 1993 Apr 15;148(1):48-59. doi: 10.1006/cimm.1993.1090.

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Peripheral immunophenotypes in children with multisystem inflammatory syndrome associated with SARS-CoV-2 infection.与 SARS-CoV-2 感染相关的儿童多系统炎症综合征的外周免疫表型。

Nat Med. 2020 Nov;26(11):1701-1707. doi: 10.1038/s41591-020-1054-6. Epub 2020 Aug 18.

Increased Complement Receptor-3 levels in monocytes and granulocytes distinguish COVID-19 patients with pneumonia from those with mild symptoms.在单核细胞和粒细胞中，补体受体 3 水平的升高可将患有肺炎的 COVID-19 患者与症状较轻的患者区分开来。

Int J Infect Dis. 2020 Oct;99:381-385. doi: 10.1016/j.ijid.2020.08.004. Epub 2020 Aug 6.

Screening and Severity of Coronavirus Disease 2019 (COVID-19) in Children in Madrid, Spain.西班牙马德里儿童新型冠状病毒肺炎（COVID-19）的筛查与严重程度

JAMA Pediatr. 2020 Apr 8. doi: 10.1001/jamapediatrics.2020.1346.

Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study.中国武汉成人 COVID-19 住院患者的临床病程和死亡危险因素：一项回顾性队列研究。

Lancet. 2020 Mar 28;395(10229):1054-1062. doi: 10.1016/S0140-6736(20)30566-3. Epub 2020 Mar 11.

Dysregulation of Immune Response in Patients With Coronavirus 2019 (COVID-19) in Wuhan, China.中国武汉 2019 年冠状病毒病（COVID-19）患者免疫反应失调。

Clin Infect Dis. 2020 Jul 28;71(15):762-768. doi: 10.1093/cid/ciaa248.

Reducing mortality from 2019-nCoV: host-directed therapies should be an option.降低2019新型冠状病毒所致死亡率：宿主导向疗法应成为一种选择。

Lancet. 2020 Feb 22;395(10224):e35-e36. doi: 10.1016/S0140-6736(20)30305-6. Epub 2020 Feb 5.

LFA-1 (CD11a/CD18) and Mac-1 (CD11b/CD18) distinctly regulate neutrophil extravasation through hotspots I and II.LFA-1（CD11a/CD18）和 Mac-1（CD11b/CD18）通过热点 I 和 II 分别调节中性粒细胞的渗出。

Exp Mol Med. 2019 Apr 9;51(4):1-13. doi: 10.1038/s12276-019-0227-1.

Accuracy of neutrophil CD64 expression in diagnosing infection in patients with autoimmune diseases: a meta-analysis.中性粒细胞 CD64 表达在诊断自身免疫性疾病患者感染中的准确性：一项荟萃分析。

Clin Rheumatol. 2019 May;38(5):1319-1328. doi: 10.1007/s10067-019-04518-0. Epub 2019 Mar 27.

Accuracy of CD64 expression on neutrophils and monocytes in bacterial infection diagnosis at pediatric intensive care admission.中性粒细胞和单核细胞 CD64 表达在儿科重症监护病房细菌感染诊断中的准确性。

Eur J Clin Microbiol Infect Dis. 2019 Jun;38(6):1079-1085. doi: 10.1007/s10096-019-03497-z. Epub 2019 Feb 2.

Neutrophil CD64 expression as a longitudinal biomarker for severe disease and acute infection in critically ill patients.中性粒细胞CD64表达作为危重症患者严重疾病和急性感染的纵向生物标志物。

Int J Lab Hematol. 2016 Oct;38(5):576-84. doi: 10.1111/ijlh.12545. Epub 2016 Aug 27.

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Innate cell response in severe SARS-CoV-2 infection in children: Expression analysis of CD64, CD18 and CD11a.

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