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冠状动脉内支架置入后纵向的伸长或缩短:何者占主导?

Longitudinal stent elongation or shortening after deployment in the coronary arteries: which is dominant?

作者信息

Algowhary Magdy, Abdelmegid Mohammed Aboel-Kassem F

机构信息

Department of Cardiovascular Medicine, Assiut University Heart Hospital, Faculty of Medicine, Assiut University, Asyut, 71515, Egypt.

出版信息

Egypt Heart J. 2021 May 17;73(1):46. doi: 10.1186/s43044-021-00170-9.

Abstract

BACKGROUND

Stent manufacturers always record stent shortening data while they do not record stent elongation data. The aim of this study is to identify both stent shortening and elongation occurring after deployment in the coronary arteries and know their percentage.

RESULTS

The length of coronary stents was measured by intravascular ultrasound (IVUS) by (1) edge-to-edge (E-E) length, measured from the appearance of the first distal strut to the last proximal strut, and (2) area-to-area (A-A) length, measured from the first distal struts seen at more than one IVUS quadrant to the last proximal struts seen at more than one IVUS quadrant. Stent shortening was defined as both E-E and A-A lengths were shorter than the manufacturer box-stated length (shortened group). Stent elongation was defined as both E-E and A-A lengths were longer than the manufacturer box-stated length (elongated group), otherwise unchanged group. Consecutive 102 stents deployed in ischemic patients were included. Stent elongation was detected in 67.6% (69 stents), and shortening was detected in 15.7% (16 stents), while unchanged stents were detected in 16.7% (17 stents). Although the 3 groups had similar box-stated length and predicted foreshortened length, they had significantly different measurements by IVUS, p<0.001 for each comparison. Differences from box-stated length were 1.9±1.4mm, -1.4±0.4mm, and 0.4±0.3mm, respectively, p<0.001. The elongated group had significantly longer differences from the corresponding box-stated and predicted foreshortened lengths, while the shortened group had significantly shorter differences from the corresponding box-stated length and similar foreshortened length. By multinomial regression analysis, the plaque-media area and stent deployment pressure were the independent predictors of the stent length groups, p=0.015 and p=0.026, respectively.

CONCLUSIONS

Change in stent length is not only shortening-as mentioned in the manufacturer documents-but also stent elongation. Stent elongation is dominant, and the most important predictors of longitudinal stent changes are plaque-media area and stent deployment pressure.

摘要

背景

支架制造商总是记录支架缩短数据,却不记录支架伸长数据。本研究的目的是确定冠状动脉内支架植入后发生的支架缩短和伸长情况,并了解其发生率。

结果

通过血管内超声(IVUS)测量冠状动脉支架的长度,方法如下:(1)边缘到边缘(E-E)长度,从第一个远端支架出现处测量至最后一个近端支架;(2)面积到面积(A-A)长度,从在多个IVUS象限中看到的第一个远端支架测量至在多个IVUS象限中看到的最后一个近端支架。支架缩短定义为E-E长度和A-A长度均短于制造商包装盒标明的长度(缩短组)。支架伸长定义为E-E长度和A-A长度均长于制造商包装盒标明的长度(伸长组),否则为无变化组。纳入了102例连续植入缺血患者体内的支架。检测到67.6%(69个支架)发生支架伸长,15.7%(16个支架)发生缩短,16.7%(17个支架)无变化。尽管三组的包装盒标明长度和预计缩短长度相似,但通过IVUS测量,它们有显著差异,每次比较p<0.001。与包装盒标明长度的差异分别为1.9±1.4mm、-1.4±0.4mm和0.4±0.3mm,p<0.001。伸长组与相应的包装盒标明长度和预计缩短长度的差异显著更长,而缩短组与相应的包装盒标明长度的差异显著更短,且缩短长度相似。通过多项回归分析,斑块-中膜面积和支架植入压力是支架长度分组的独立预测因素,p分别为0.015和0.026。

结论

支架长度的变化不仅有制造商文件中提到的缩短,还有支架伸长。支架伸长占主导,纵向支架变化的最重要预测因素是斑块-中膜面积和支架植入压力。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b08e/8128949/3d5d7ace20ee/43044_2021_170_Fig1_HTML.jpg

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