CAS Key Laboratory of Tropical Plant Resources and Sustainable Use, Xishuangbanna Tropical Botanical Garden, Chinese Academy of Sciences, Kunming, China.
University of Chinese Academy of Sciences, Beijing, China.
Nat Prod Res. 2022 Oct;36(20):5235-5240. doi: 10.1080/14786419.2021.1928119. Epub 2021 May 21.
Two previously unreported monoterpenoid indole alkaloids, 19(20)-5-carboxymethylvallesiachotamine () and 19(20)-5-carboxymethylvallesiachotamine (), along with five known indole alkaloids (-) were isolated from stems. Their structures were characterized by extensive spectroscopic data. Among these isolates, compounds and were the two new Δ geometric isomers. The anti-inflammatory activities in vitro of all isolated compounds were evaluated using NO assay.[Formula: see text].
从 茎中分离得到两种以前未报道的单萜吲哚生物碱，19(20)-5-羧甲基瓦勒西亚朝塔明（）和 19(20)-5-羧甲基瓦勒西亚朝塔明（），以及五种已知的吲哚生物碱（-）。通过广泛的光谱数据对它们的结构进行了表征。在这些分离物中，化合物和是两种新的 Δ 几何异构体。采用 NO 测定法评价了所有分离化合物的体外抗炎活性。[公式：见正文]。
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