Jha Abhishek, Vasques Francesco, Sanderson Barnaby, Daly Kathleen, Glover Guy, Ioannou Nicholas, Wyncoll Duncan, Sherren Peter, Langrish Chris, Meadows Chris, Retter Andrew, Paul Richard, Barrett Nicholas A, Camporota Luigi
Cardiothoracic Intensive Care Unit, St George's Hospitals NHS Foundation Trust, London, UK.
Guy's and Saint Thomas' NHS Foundation Trust, London, UK.
J Intensive Care Soc. 2021 May;22(2):175-181. doi: 10.1177/1751143720928895. Epub 2020 Jun 1.
The variability of acute respiratory distress syndrome management may affect the referral practice to severe respiratory failure centres. We described the management of acute respiratory distress syndrome in our catchment area.
An electronic survey was administered to 42 intensive care units in South-East England.
Response rate was 71.4%. High-flow nasal oxygen and non-invasive ventilation were used 'often' in moderate-acute respiratory distress syndrome by 46.7% and 60%. During invasive ventilation, 90% preferred pressure control, targeting tidal volumes of 6-8 ml/kg (53.3%) or 4-6 ml/kg (46.7%). Positive end-expiratory pressure was selected by positive end-expiratory pressure/inspiratory fraction of oxygen tables (50%) or decremental positive end-expiratory pressure trials (20%). Neuro-muscular blockers were widely used, although routinely by only 3.3%. High-frequency oscillatory ventilation (10%) and inhaled nitric oxide (13.3%) were rarely used. None used oesophageal manometry. Recruitment manoeuvres were used 'often' by 26.7%. Equipment (90%) and protocols (80%) for prone position were common, with sessions mostly lasting 12-18 h.
Although variable, practice well reflected the available evidence. Proning was widely practiced with good availability of educational resources and protocolised care.
急性呼吸窘迫综合征管理的变异性可能会影响向严重呼吸衰竭中心的转诊实践。我们描述了我们所负责区域内急性呼吸窘迫综合征的管理情况。
对英格兰东南部的42个重症监护病房进行了电子调查。
回复率为71.4%。在中度急性呼吸窘迫综合征中,46.7%的机构“经常”使用高流量鼻导管给氧,60%的机构“经常”使用无创通气。在有创通气期间,90%的机构倾向于压力控制,目标潮气量为6 - 8 ml/kg(53.3%)或4 - 6 ml/kg(46.7%)。呼气末正压通过呼气末正压/吸入氧分数表(50%)或递减呼气末正压试验(20%)来选择。神经肌肉阻滞剂被广泛使用,但常规使用的仅占3.3%。高频振荡通气(10%)和吸入一氧化氮(13.3%)很少使用。没有机构使用食管测压法。26.7%的机构“经常”使用肺复张手法。用于俯卧位的设备(90%)和方案(80%)很常见,疗程大多持续12 - 18小时。
尽管存在差异,但实践很好地反映了现有证据。俯卧位通气广泛应用,教育资源和规范化护理的可及性良好。