Afzali Abolfazl, Goli Shahrbanoo, Moravveji Alireza, Bagheri Hossein, Mirhosseini Seyedmohammad, Ebrahimi Hossein
Student Research Committee, School of Nursing & Midwifery Shahroud University of Medical Sciences Shahroud Iran.
Department of Epidemiology and Biostatistics, School of Public Health Shahroud University of Medical Sciences Shahroud Iran.
Health Sci Rep. 2021 May 19;4(2):e301. doi: 10.1002/hsr2.301. eCollection 2021 Jun.
Fatigue is one of the most common complaints of the elderly. This study was conducted to assess the effect of zinc supplements on fatigue among the elderly.
This randomized clinical trial was conducted on 150 elderly aged ≥60 years who were recruited from the health centers (Kashan, Iran) with a convenience sampling method. Participants were allocated to intervention and control groups by block randomization. Participants in the intervention group received a daily dose of 30 mg of zinc supplement for 70 days; meanwhile, in the control group, no intervention was performed. The level of fatigue was measured by the multidimensional fatigue inventory before and after the intervention. Both groups were homogeneous in terms of demographic variables, fatigue, and serum zinc level before the intervention. The significance level was considered as 0.05 in all tests.
Zinc supplementation significantly reduced fatigue (mean difference: -10.41 vs 1.37, < .001) and increased serum zinc level (mean difference: 14.22, vs -0.57, < .001) compared to the control group.
Consumption of zinc supplements for the elderly is recommended to overcome fatigue.
疲劳是老年人最常见的主诉之一。本研究旨在评估补充锌对老年人疲劳的影响。
本随机临床试验对150名年龄≥60岁的老年人进行，这些老年人通过便利抽样法从健康中心（伊朗卡尚）招募。参与者通过整群随机化分配到干预组和对照组。干预组参与者每天服用30毫克锌补充剂，持续70天；同时，对照组不进行干预。干预前后通过多维疲劳量表测量疲劳程度。两组在干预前的人口统计学变量、疲劳程度和血清锌水平方面具有同质性。所有检验的显著性水平均设定为0.05。
与对照组相比，补充锌显著降低了疲劳程度（平均差值：-10.41对1.37，P<0.001），并提高了血清锌水平（平均差值：14.22对-0.57，P<0.001）。
建议老年人服用锌补充剂以克服疲劳。
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