German Biobank Node, Charité Universitätsmedizin Berlin, Berlin, Germany.
Leipzig Medical Biobank, University Leipzig, Leipzig, Germany.
Eur J Hum Genet. 2022 Dec;30(12):1344-1354. doi: 10.1038/s41431-021-00905-x. Epub 2021 May 24.
Biobanks are important infrastructures facilitating biomedical research. After a decade of rolling out such infrastructures, a shift in attention to the sustainability of biobanks could be observed in recent years. In this regard, an increase in the as yet relatively low utilisation rates of biobanks has been formulated as a goal. Higher utilisation rates can only be achieved if the perspectives of potential users of biobanks-particularly researchers not yet collaborating with biobanks-are adequately considered. To better understand their perspectives, a survey was conducted at ten different research institutions in Germany hosting a centralised biobank. The survey targeted potential users of biobank services, i.e. researchers working with biosamples. It addressed the general demand for biosamples, strategies for biosample acquisition/storage and reasons for/against collaborating with biobanks. In total, 354 researchers filled out the survey. Most interestingly, only a minority of researchers (12%) acquired their biosamples via biobanks. Of the respondents not collaborating with biobanks on sample acquisition, around half were not aware of the (services of the) respective local biobank. Those who actively decided against acquiring biosamples via a biobank provided different reasons. Most commonly, respondents stated that the biosamples required were not available, the costs were too high and information about the available biosamples was not readily accessible. Biobanks can draw many lessons from the results of the survey. Particularly, external communication and outreach should be improved. Additionally, biobanks might have to reassess whether their particular collection strategies are adequately aligned with local researchers' needs.
生物库是促进生物医学研究的重要基础设施。经过十年的基础设施建设,近年来人们对生物库的可持续性的关注发生了转变。在这方面,提高生物库的利用率被提上了议程,尽管目前的利用率相对较低。只有当生物库的潜在用户(特别是尚未与生物库合作的研究人员)的观点得到充分考虑时,才能提高利用率。为了更好地了解他们的观点,在德国的十个不同的研究机构中进行了一项针对中央生物库的潜在用户的调查。该调查针对的是生物库服务的潜在用户,即使用生物样本的研究人员。它涉及对生物样本的一般需求、生物样本获取/存储策略以及与生物库合作的原因和反对原因。共有 354 名研究人员填写了调查问卷。最有趣的是,只有少数研究人员(12%)通过生物库获取他们的生物样本。在那些不合作获取样本的受访者中,约有一半人不知道当地生物库的(服务)。那些积极决定不通过生物库获取生物样本的人提供了不同的理由。最常见的是,受访者表示所需的生物样本不可用,成本太高,而且可用生物样本的信息不易获得。生物库可以从调查结果中吸取许多教训。特别是,应该改进外部沟通和外联工作。此外,生物库可能不得不重新评估其特定的收集策略是否与当地研究人员的需求充分一致。