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使用颅内引流管作为治疗颅内中间型链球菌脓肿的通道。

Use of an Intracranial Drain as a Conduit for Treatment of an Intracranial Streptococcus intermedius Abscess.

作者信息

Lallani Shoeb B, Hyte Melanie, Trieu Emily, Reyes-Sacin Carlos, Doan Ninh

机构信息

Neurology, University of Alabama at Birmingham School of Medicine, Birmingham, USA.

Pharmacology, Baptist Medical Center South, Montgomery, USA.

出版信息

Cureus. 2021 Apr 21;13(4):e14613. doi: 10.7759/cureus.14613.

Abstract

Brain abscesses are difficult to manage clinically and often result in a poor outcome. Although surgical and medical therapeutics have progressed, there are still challenges that make treating intracranial abscesses problematic. One of these treatment barriers is the poor penetration of intravenous antibiotics to the infection source through the blood-brain barrier. In this case report, we will discuss the use of a surgical drain as a conduit for direct antibiotic administration for a rare, recurrent infection. This technique allows us to bypass the blood-brain barrier while also reducing the systemic effects of antibiotics. When used in conjunction with craniotomy and resection, direct antibiotic administration via a surgical drain proved to be effective at treating our patient's abscess and preventing recurrence.

摘要

脑脓肿在临床上难以处理,且常常导致不良后果。尽管外科和药物治疗已有进展,但仍存在一些挑战,使得颅内脓肿的治疗存在问题。这些治疗障碍之一是静脉注射抗生素通过血脑屏障到达感染源的穿透性较差。在本病例报告中,我们将讨论使用外科引流管作为直接给予抗生素治疗罕见复发性感染的途径。该技术使我们能够绕过血脑屏障,同时还能降低抗生素的全身效应。当与开颅手术和切除术联合使用时,经外科引流管直接给予抗生素被证明对治疗我们患者的脓肿并预防复发有效。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/baca/8139600/a658e491370f/cureus-0013-00000014613-i01.jpg

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