Institut de Cancérologie de l'Ouest, Angers, France.
LARIS Systems Engineering Research Laboratory, University of Angers, Angers, France.
J Appl Clin Med Phys. 2021 Jun;22(6):154-161. doi: 10.1002/acm2.13256. Epub 2021 May 27.
The aim of this study is to provide and test a new methodology to adjust the AcurosXB beam model for VMAT treatment plans.
The effective target spot size of the AcurosXB v15 algorithm was adjusted in order to minimize the difference between calculated and measured penumbras. The dosimetric leaf gap (DLG) was adjusted using the asynchronous oscillating sweeping gap tests defined in the literature and the MLC transmission was measured. The impact of the four parameters on the small field output factors was assessed using a design of experiment methodology. Patient quality controls were performed for the three beam models investigated including two energies and two MLC models.
Effective target spot sizes differed from the manufacturer recommendations and strongly depended on the MLC model considered. DLG values ranged from 0.7 to 2.3 mm and were found to be larger than the ones based on the sweeping gap tests. All parameters were found to significantly influence the calculated output factors, especially for the 0.5 cm × 0.5 cm field size. Interactions were also identified for fields smaller than 2 cm × 2 cm, suggesting that adjusting the parameters on the small field output factors should be done with caution. All patient quality controls passed the universal action limit of 90%.
The methodology provided is simple to implement in clinical practice. It was validated for three beam models covering a large variety of treatment types and localizations.
本研究旨在提供并测试一种新的方法,以调整 AcurosXB 射束模型用于 VMAT 治疗计划。
调整 AcurosXB v15 算法的有效靶区大小,以最小化计算和测量的半影之间的差异。使用文献中定义的异步摆动扫描间隙测试调整剂量学叶间隙(DLG),并测量 MLC 传输。使用实验设计方法评估四个参数对小射野输出因子的影响。对三种光束模型进行了患者质量控制,包括两种能量和两种 MLC 模型。
有效靶区大小与制造商的建议不同,并且强烈依赖于所考虑的 MLC 模型。DLG 值范围为 0.7 至 2.3 毫米,发现比基于扫描间隙测试的 DLG 值大。所有参数都被发现显著影响计算的输出因子,特别是对于 0.5 厘米×0.5 厘米的射野大小。在小于 2 厘米×2 厘米的射野中也发现了相互作用,这表明在小射野输出因子上调整参数时应谨慎。所有患者质量控制都通过了 90%的通用行动限值。
提供的方法在临床实践中易于实施。它已经过三种光束模型的验证,涵盖了多种治疗类型和定位。