Lebanese American University, School of Engineering, Department of ECE, Byblos, Lebanon.
Near East University, Nicosia/TRNC, Mersin-10, 99138, Turkey.
Comput Math Methods Med. 2021 May 10;2021:5527271. doi: 10.1155/2021/5527271. eCollection 2021.
The reverse transcriptase polymerase chain reaction (RT-PCR) is still the routinely used test for the diagnosis of SARS-CoV-2 (COVID-19). However, according to several reports, RT-PCR showed a low sensitivity and multiple tests may be required to rule out false negative results. Recently, chest computed tomography (CT) has been an efficient tool to diagnose COVID-19 as it is directly affecting the lungs. In this paper, we investigate the application of pre-trained models in diagnosing patients who are positive for COVID-19 and differentiating it from normal patients, who tested negative for coronavirus. The study aims to compare the generalization capabilities of deep learning models with two thoracic radiologists in diagnosing COVID-19 chest CT images. A dataset of 3000 images was obtained from the Near East Hospital, Cyprus, and used to train and to test the three employed pre-trained models. In a test set of 250 images used to evaluate the deep neural networks and the radiologists, it was found that deep networks (ResNet-18, ResNet-50, and DenseNet-201) can outperform the radiologists in terms of higher accuracy (97.8%), sensitivity (98.1%), specificity (97.3%), precision (98.4%), and F1-score (198.25%), in classifying COVID-19 images.
逆转录聚合酶链反应 (RT-PCR) 仍然是 SARS-CoV-2(COVID-19)诊断的常规测试。然而,根据多项报道,RT-PCR 显示出低灵敏度,可能需要多次测试才能排除假阴性结果。最近,胸部计算机断层扫描 (CT) 已成为诊断 COVID-19 的有效工具,因为它直接影响肺部。在本文中,我们研究了预训练模型在诊断 COVID-19 阳性患者和区分 COVID-19 阴性患者方面的应用。该研究旨在比较深度学习模型与两名胸部放射科医生在诊断 COVID-19 胸部 CT 图像方面的泛化能力。从塞浦路斯的近东医院获得了一个包含 3000 张图像的数据集,用于训练和测试所使用的三个预训练模型。在用于评估深度神经网络和放射科医生的 250 张图像测试集中,发现深度网络(ResNet-18、ResNet-50 和 DenseNet-201)在分类 COVID-19 图像方面可以优于放射科医生,具有更高的准确性(97.8%)、敏感性(98.1%)、特异性(97.3%)、精度(98.4%)和 F1 分数(198.25%)。