Alonso Pérez Jose Luis, Martín Pérez Sebastián, Battaglino Andrea, Villafañe Jorge H, Alonso-Sal Alexandra, Sánchez Romero Eleuterio A
Musculoskeletal Pain and Motor Control Research Group, Faculty of Health Sciences, Universidad Europea de Madrid, 28670 Madrid, Spain.
Department of Physiotherapy, Faculty of Biomedical and Health Sciences, Universidad Europea de Madrid, Tajo, s/n, Urbanización El Bosque, Villaviciosa de Odón, 28670 Madrid, Spain.
J Clin Med. 2021 May 21;10(11):2229. doi: 10.3390/jcm10112229.
Osteoporosis (OP) is a systemic disease that is characterized by decreased bone density and quality. : The purpose of this systematic review was to determine the effects of muscle strengthening exercise in postmenopausal women with OP. : A literature search was conducted systematically in MEDLINE, CINAHL, EMBASE databases for human studies up to 31 March 2021. Two researchers screened the articles against predefined inclusion criteria; a third resolved discrepancies. Articles were included if they assessed the effects of muscle strengthening exercise in postmenopausal women with OP. The protocol for this systematic review was registered on PROSPERO (CRD42021207917) and a qualitative systematic review was carried out following the PRISMA statement. Methodological quality was evaluated through the scientific validity scales PEDro. Finally, RTCs and NRCTs risk of bias was assessed with the Cochrane risk of bias tool (Risk of Bias-ROB 2.0) and ROBINS-1, respectively. : A total of 16 studies (1028 subjects) that met the different eligibility criteria previously established were selected. There is evidence of good methodological quality and a low to moderate risk of bias that supports that muscle strengthening exercise alone or in combination with other therapeutic modalities improves BMD (9, = 401) in proximal femur and lumbar vertebra body, muscle strength (10, = 558), balance (4, = 159), functionality (7, = 617), and quality of life (5, = 291).
Exercise programs focused on muscle strengthening have benefits for all variables studied in postmenopausal women with OP.
骨质疏松症(OP)是一种以骨密度和质量下降为特征的全身性疾病。本系统评价的目的是确定肌肉强化运动对绝经后骨质疏松症女性的影响。截至2021年3月31日,在MEDLINE、CINAHL、EMBASE数据库中系统检索了关于人体研究的文献。两名研究人员根据预先确定的纳入标准筛选文章;第三名研究人员解决分歧。如果文章评估了肌肉强化运动对绝经后骨质疏松症女性的影响,则将其纳入。本系统评价的方案已在PROSPERO(CRD42021207917)上注册,并按照PRISMA声明进行了定性系统评价。通过PEDro科学有效性量表评估方法学质量。最后,分别使用Cochrane偏倚风险工具(偏倚风险-ROB 2.0)和ROBINS-1评估随机对照试验(RTCs)和非随机对照试验(NRCTs)的偏倚风险。共选择了16项符合先前确定的不同纳入标准的研究(1028名受试者)。有证据表明方法学质量良好,偏倚风险低至中度,支持单独进行肌肉强化运动或与其他治疗方式联合进行可改善股骨近端和腰椎椎体的骨密度(9项研究,n = 401)、肌肉力量(10项研究,n = 558)、平衡能力(4项研究,n = 159)、功能(7项研究,n = 617)和生活质量(5项研究,n = 291)。
针对肌肉强化的运动计划对绝经后骨质疏松症女性研究的所有变量均有益处。