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空气污染增加波兰儿童上呼吸道症状的发病率。

Air Pollution Increases the Incidence of Upper Respiratory Tract Symptoms among Polish Children.

作者信息

Ratajczak Aleksandra, Badyda Artur, Czechowski Piotr Oskar, Czarnecki Adam, Dubrawski Michał, Feleszko Wojciech

机构信息

Department of Pediatric Respiratory Diseases and Allergy, Medical University of Warsaw, Żwirki i Wigury 63A, 02-091 Warsaw, Poland.

Department of Informatics and Environment Quality Research, Faculty of Building Services, Hydro- and Environmental Engineering, Warsaw University of Technology, 20 Nowowiejska Street, 00-653 Warsaw, Poland.

出版信息

J Clin Med. 2021 May 16;10(10):2150. doi: 10.3390/jcm10102150.

Abstract

A substantial proportion of airway disease's global burden is attributable to exposure to air pollution. This study aimed to investigate the association between air pollution, assessed as concentrations of particulate matter PM2.5 and PM10 on the upper respiratory tract symptoms (URTS) in children. A nation-wide, questionnaire-based study was conducted in Poland in winter 2018/2019 in a population of 1475 children, comparing URTS throughout the study period with publicly available data on airborne particulate matter. A general regression model was used to evaluate the lag effects between daily changes in PM10 and PM2.5 and the number of children reporting URTS and their severity. PM10 and PM2.5 in the single-pollutant models had significant effects on the number of children reporting URTS. The prevalence of URTS: "runny nose", "sneezing" and "cough" was positively associated with 12-week mean PM2.5 and PM10 concentrations. In the locations with the highest average concentration of PM, the symptoms of runny nose, cough and sneezing were increased by 10%, 9% and 11%, respectively, compared to the cities with the lowest PM concentrations. This study showed that moderate-term exposure (12 week observation period) to air pollution was associated with an increased risk of URTS among children aged 3-12 years in Poland. These findings may influence public debate and future policy at the national and international levels to improve air quality in cities and improve children's health.

摘要

全球很大一部分气道疾病负担可归因于空气污染暴露。本研究旨在调查空气污染(以细颗粒物PM2.5和可吸入颗粒物PM10的浓度评估)与儿童上呼吸道症状(URTS)之间的关联。2018/2019年冬季在波兰开展了一项全国性的基于问卷的研究,研究对象为1475名儿童,将整个研究期间的上呼吸道症状与公开可得的空气中颗粒物数据进行比较。使用一般回归模型来评估PM10和PM2.5的每日变化与报告上呼吸道症状的儿童数量及其严重程度之间的滞后效应。单污染物模型中的PM10和PM2.5对报告上呼吸道症状的儿童数量有显著影响。上呼吸道症状“流鼻涕”“打喷嚏”和“咳嗽”的患病率与12周平均PM2.5和PM10浓度呈正相关。与PM浓度最低的城市相比,在PM平均浓度最高的地区,流鼻涕、咳嗽和打喷嚏的症状分别增加了10%、9%和11%。本研究表明,在波兰,3至12岁儿童中期暴露于空气污染(12周观察期)与上呼吸道症状风险增加有关。这些发现可能会影响国家和国际层面的公众辩论及未来政策,以改善城市空气质量并增进儿童健康。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/689d/8156299/acea3b17bb70/jcm-10-02150-g001.jpg

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