Division of Infectious Diseases, Department of Medicine, University of Toronto, Toronto, ON, Canada.
Toronto General Hospital Research Institute, University Health Network, 200 Elizabeth Street, Room 13EN214, Toronto, ON, M5G2C4, Canada.
Curr HIV/AIDS Rep. 2021 Aug;18(4):280-288. doi: 10.1007/s11904-021-00564-z. Epub 2021 Jun 6.
To highlight recent trends in the epidemiology of HIV and syphilis, the impact of the COVID epidemic, our approach to care of co-infected patients, and our views on important next steps in advancing the field.
HIV and syphilis co-infection has been on the rise in recent years although since the COVID pandemic there is a decrease in new diagnoses-it remains unclear if this represents a true decline or inadequate testing or under-reporting. Standard HIV care should include regular syphilis serology .Treatment and serological follow-up of syphilis in HIV positive and negative patients can be conducted similarly. Challenges remain in the diagnosis and management of neurosyphilis. New models for testing and prevention will be crucial next steps in controlling co-infection. The intersection of HIV and syphilis infections continues to pose new and unique challenges in diagnosis, treatment, and prevention.
强调艾滋病病毒和梅毒流行病学的近期趋势、COVID-19 疫情的影响、我们对合并感染患者护理的方法以及我们对推进该领域的重要下一步的看法。
尽管自 COVID-19 大流行以来,新诊断病例有所减少,但近年来艾滋病病毒和梅毒合并感染呈上升趋势——目前尚不清楚这是否代表真正的下降,还是检测不足或报告不足。标准的艾滋病毒护理应包括定期梅毒血清学检查。对 HIV 阳性和阴性患者的梅毒进行治疗和血清学随访可以类似地进行。在诊断和管理神经梅毒方面仍然存在挑战。检测和预防的新模式将是控制合并感染的关键下一步。艾滋病毒和梅毒感染的交叉继续在诊断、治疗和预防方面带来新的和独特的挑战。