Mandelbaum B R, Tolo V T, McAfee P C, Burest P
University of California School of Medicine, Division of Orthopaedic Surgery, Los Angeles 90024.
Clin Orthop Relat Res. 1988 Sep(234):5-11.
The nutritional status was analyzed in 37 patients being treated with staged anterior and posterior spinal reconstructive procedures. Using stringent criteria for nutritional and immunologic incompetency, 31 patients (84%) became malnourished during hospitalization. Although the serum albumin on admission had been normal for all patients, it became significantly depressed in 77% following anterior and posterior spinal procedures. In a similar fashion, the total lymphocyte count became significantly depressed in 92%. The postoperative complications were clearly more extensive in patients who were malnourished and immune-deficient using these criteria--15 patients with urinary tract infections, four patients with bacterial sepsis, four patients with wound infections, and four patients with pneumonia (vs. one with a wound infection in the adequately nourished group). The length of hospitalization following the second operative procedure was significantly longer in the malnourished group: 16.2 days versus 12.4 days (p less than 0.05). The main purpose of this study is to create awareness of the ongoing nutritional demands placed on patients treated by two-stage spinal reconstruction surgical procedures. More aggressive nutritional intervention can reduce postoperative complications and length of hospital stay and improve the speed of functional recovery.
对37例接受前后路分期脊柱重建手术治疗的患者的营养状况进行了分析。采用严格的营养和免疫功能不全标准,31例患者(84%)在住院期间出现营养不良。尽管所有患者入院时血清白蛋白均正常,但在接受前后路脊柱手术后,77%的患者血清白蛋白显著降低。同样,92%的患者总淋巴细胞计数显著降低。根据这些标准,营养不良和免疫缺陷患者的术后并发症明显更多——15例患者发生尿路感染,4例患者发生细菌性败血症,4例患者发生伤口感染,4例患者发生肺炎(而营养状况良好组仅有1例发生伤口感染)。营养不良组在第二次手术后的住院时间明显更长:16.2天对12.4天(p<0.05)。本研究的主要目的是让人们认识到接受两阶段脊柱重建手术治疗的患者持续存在的营养需求。更积极的营养干预可以减少术后并发症和住院时间,并提高功能恢复速度。