大脑中的蛋白病损：超级老龄黑猩猩（Pan troglodytes）的案例研究。
Proteopathic lesions in the brain of a super-aged chimpanzee (Pan troglodytes).
机构信息
Department of Veterinary Medicine, Tokyo University of Agriculture and Technology, Tokyo, Japan.
Hiwa Museum for Natural History, Hiroshima, Japan.
出版信息
J Med Primatol. 2021 Aug;50(4):222-224. doi: 10.1111/jmp.12530. Epub 2021 Jun 7.
PMID:34096618
Abstract
The brain of a chimpanzee estimated to be 68 years old, the oldest reported so far, has been examined. Pathological analyses revealed the formation of mild tau-positive neuritic clusters and cytoplasmic α-synuclein aggregates, in addition to severe cerebral amyloid angiopathy and diffuse plaques, but no tangle lesions were observed.
摘要
对一只估计年龄为 68 岁的黑猩猩大脑进行了检查，这是迄今为止报道的最年长的大脑。病理分析显示，除了严重的脑淀粉样血管病和弥漫性斑块外，还形成了轻度 tau 阳性神经突簇和细胞质 α-突触核蛋白聚集物，但未观察到缠结病变。
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