Institute for Social Research, University of Michigan, Ann Arbor, Michigan.
Center for the Study of Drugs, Alcohol, Smoking and Health, School of Nursing, University of Michigan, Ann Arbor, Michigan.
J Stud Alcohol Drugs. 2021 May;82(3):362-367. doi: 10.15288/jsad.2021.82.362.
The purpose of this longitudinal study was to identify associations of drinking intensity at age 29/30 with symptoms of alcohol use disorder (AUD) at age 35.
Analyses used national longitudinal data from 1,253 individuals (53.5% female) participating in the Monitoring the Future study. Age 29/30 data were collected from 2005 to 2013; age 35 data were collected from 2010 to 2018. Multivariable models regressed age 35 past-5-year AUD symptoms (vs. nondisordered drinking/abstinence) on age 29/30 past-2-week drinking intensity (no/low [0-4] drinking, binge [5-9] drinking, high-intensity [10+] drinking), with key covariates being controlled for.
At age 35, 32.6% (SE = 1.50) of respondents reported AUD symptoms. AUD symptoms at age 35 were reported by 77.5% (SE = 4.79) of participants who reported age 29/30 high-intensity drinking and 60.6% (SE = 3.95) of participants who reported age 29/30 binge drinking. Age 35 past-5-year abstinence was reported by almost no respondents reporting age 29/30 binge drinking or high-intensity drinking. AUD symptoms at age 35 were significantly more likely for those who reported binge (adjusted multivariable odds ratio [AOR] = 5.61, 95% CI [3.79, 8.30], p < .001) or high-intensity (AOR = 12.26, 95% CI [6.70, 22.41], p < .001) drinking versus no/low drinking at age 29/30. The likelihood of having AUD symptoms was significantly higher for high-intensity than for binge drinkers (AOR = 2.18, 95% CI [1.14, 4.19], p = .019).
Nearly 80% of those young adults who reported engaging in high-intensity drinking (10+ drinks in a row) at age 29/30 later reported AUD symptoms at age 35. High-intensity drinking appears to be a strong prospective marker of risk for AUD symptoms among adults in the United States.
本纵向研究旨在确定 29/30 岁时的饮酒强度与 35 岁时的酒精使用障碍(AUD)症状之间的关联。
分析使用了来自参加“监测未来”研究的 1253 名个体(53.5%为女性)的全国性纵向数据。29/30 岁的数据于 2005 年至 2013 年收集;35 岁的数据于 2010 年至 2018 年收集。使用多变量模型,根据年龄 29/30 岁过去 2 周的饮酒强度(无/低[0-4]饮酒、狂欢[5-9]饮酒、高强度[10+]饮酒),回归分析了年龄 35 岁过去 5 年 AUD 症状(与无紊乱饮酒/戒酒相比),同时控制了关键协变量。
在 35 岁时,32.6%(SE=1.50)的受访者报告了 AUD 症状。在报告年龄 29/30 岁高强度饮酒的参与者中,有 77.5%(SE=4.79)报告了 AUD 症状,在报告年龄 29/30 岁狂欢饮酒的参与者中,有 60.6%(SE=3.95)报告了 AUD 症状。报告年龄 29/30 岁狂欢或高强度饮酒的参与者中,几乎没有人报告年龄 35 岁过去 5 年戒酒。与年龄 29/30 岁无/低饮酒相比,年龄 35 岁时 AUD 症状更有可能报告狂欢(调整后的多变量优势比[AOR]=5.61,95%置信区间[3.79,8.30],p<0.001)或高强度(AOR=12.26,95%置信区间[6.70,22.41],p<0.001)饮酒。与年龄 29/30 岁无/低饮酒相比,高强度饮酒者(AOR=2.18,95%置信区间[1.14,4.19],p=0.019)更有可能出现 AUD 症状。
近 80%的年轻人在 29/30 岁时报告高强度饮酒(连续饮酒 10 杯以上),后来在 35 岁时报告 AUD 症状。高强度饮酒似乎是美国成年人 AUD 症状的一个强有力的前瞻性风险标志物。