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29/30 岁时的饮酒强度可预测 35 岁时的酒精使用障碍症状在全国样本中的情况。

Drinking Intensity at Age 29/30 as a Predictor of Alcohol Use Disorder Symptoms at Age 35 in a National Sample.

机构信息

Institute for Social Research, University of Michigan, Ann Arbor, Michigan.

Center for the Study of Drugs, Alcohol, Smoking and Health, School of Nursing, University of Michigan, Ann Arbor, Michigan.

出版信息

J Stud Alcohol Drugs. 2021 May;82(3):362-367. doi: 10.15288/jsad.2021.82.362.

Abstract

OBJECTIVE

The purpose of this longitudinal study was to identify associations of drinking intensity at age 29/30 with symptoms of alcohol use disorder (AUD) at age 35.

METHOD

Analyses used national longitudinal data from 1,253 individuals (53.5% female) participating in the Monitoring the Future study. Age 29/30 data were collected from 2005 to 2013; age 35 data were collected from 2010 to 2018. Multivariable models regressed age 35 past-5-year AUD symptoms (vs. nondisordered drinking/abstinence) on age 29/30 past-2-week drinking intensity (no/low [0-4] drinking, binge [5-9] drinking, high-intensity [10+] drinking), with key covariates being controlled for.

RESULTS

At age 35, 32.6% (SE = 1.50) of respondents reported AUD symptoms. AUD symptoms at age 35 were reported by 77.5% (SE = 4.79) of participants who reported age 29/30 high-intensity drinking and 60.6% (SE = 3.95) of participants who reported age 29/30 binge drinking. Age 35 past-5-year abstinence was reported by almost no respondents reporting age 29/30 binge drinking or high-intensity drinking. AUD symptoms at age 35 were significantly more likely for those who reported binge (adjusted multivariable odds ratio [AOR] = 5.61, 95% CI [3.79, 8.30], p < .001) or high-intensity (AOR = 12.26, 95% CI [6.70, 22.41], p < .001) drinking versus no/low drinking at age 29/30. The likelihood of having AUD symptoms was significantly higher for high-intensity than for binge drinkers (AOR = 2.18, 95% CI [1.14, 4.19], p = .019).

CONCLUSIONS

Nearly 80% of those young adults who reported engaging in high-intensity drinking (10+ drinks in a row) at age 29/30 later reported AUD symptoms at age 35. High-intensity drinking appears to be a strong prospective marker of risk for AUD symptoms among adults in the United States.

摘要

目的

本纵向研究旨在确定 29/30 岁时的饮酒强度与 35 岁时的酒精使用障碍(AUD)症状之间的关联。

方法

分析使用了来自参加“监测未来”研究的 1253 名个体(53.5%为女性)的全国性纵向数据。29/30 岁的数据于 2005 年至 2013 年收集;35 岁的数据于 2010 年至 2018 年收集。使用多变量模型,根据年龄 29/30 岁过去 2 周的饮酒强度(无/低[0-4]饮酒、狂欢[5-9]饮酒、高强度[10+]饮酒),回归分析了年龄 35 岁过去 5 年 AUD 症状(与无紊乱饮酒/戒酒相比),同时控制了关键协变量。

结果

在 35 岁时,32.6%(SE=1.50)的受访者报告了 AUD 症状。在报告年龄 29/30 岁高强度饮酒的参与者中,有 77.5%(SE=4.79)报告了 AUD 症状,在报告年龄 29/30 岁狂欢饮酒的参与者中,有 60.6%(SE=3.95)报告了 AUD 症状。报告年龄 29/30 岁狂欢或高强度饮酒的参与者中,几乎没有人报告年龄 35 岁过去 5 年戒酒。与年龄 29/30 岁无/低饮酒相比,年龄 35 岁时 AUD 症状更有可能报告狂欢(调整后的多变量优势比[AOR]=5.61,95%置信区间[3.79,8.30],p<0.001)或高强度(AOR=12.26,95%置信区间[6.70,22.41],p<0.001)饮酒。与年龄 29/30 岁无/低饮酒相比,高强度饮酒者(AOR=2.18,95%置信区间[1.14,4.19],p=0.019)更有可能出现 AUD 症状。

结论

近 80%的年轻人在 29/30 岁时报告高强度饮酒(连续饮酒 10 杯以上),后来在 35 岁时报告 AUD 症状。高强度饮酒似乎是美国成年人 AUD 症状的一个强有力的前瞻性风险标志物。

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