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成人脊柱畸形手术后早期术后并发症和死亡率的发生率和危险因素:来自 2011 年至 2013 年国家手术质量改进计划的数据。

Incidence and Risk Factors for Early Postoperative Complications and Mortality Following Adult Spinal Deformity Surgery: Data From the National Surgical Quality Improvement Program From 2011 to 2013.

机构信息

Spine Center and Department of Orthopedic Surgery, Seoul National University College of Medicine and Seoul National University Bundang Hospital, Seoul, Republic of Korea.

Department of Orthopedic Surgery, Division of Spinal Surgery, The Och Spine Hospital at New York-Presbyterian/Allen Hospital, Columbia University, New York, NY.

出版信息

Clin Spine Surg. 2021 Dec 1;34(10):E566-E574. doi: 10.1097/BSD.0000000000001214.

Abstract

STUDY DESIGN

Retrospective cohort analysis using the American College of Surgeons National Surgical Quality Improvement Program database.

OBJECTIVE

The objective of this study was to investigate the incidence and risk factors of perioperative complications and mortality in patients undergoing adult spinal deformity (ASD) surgery.

SUMMARY OF BACKGROUND DATA

Although ASD surgery has been associated with a relatively high complication rate, a focus on perioperative complications in a large cohort has rarely been reported.

MATERIALS AND METHODS

In the database of the 2011-2013 American College of Surgeons National Surgical Quality Improvement Program database, a cohort of patients (n=1484) above 20 years and underwent ASD surgery was established by primary and other Current Procedural Terminology and International Classification of Disease, Ninth Revision codes. The incidences of perioperative (within 30 d postsurgery) minor/major complications and mortality was investigated. Risk factors for minor/major complications and mortality were assessed using logistic regression modeling.

RESULTS

Of 1484 patients undergoing ASD surgery, the overall complication rate was 15.8% (minor complications: 8.2%; major complications: 10.4%), and the mortality rate was 0.6% (9 patients). After multivariate analysis, dependent functional status [P=0.003; odds ratios (ORs), 4.838], anterior or anterior+posterior approaches (P=0.001; OR, 2.022), and prolonged operative time (>5 h) (P=0.004; OR, 1.821) were associated with an increased risk of minor complications. Male sex (P=0.013; OR, 1.567), osteotomy procedure (P=0.008; OR, 1.674) and prolonged operative time (>5 h) (P<0.001; OR, 2.142) were associated with an increased risk of major complications. The American Society of Anesthesiologists 4 status (P=0.009; OR, 34.697) was a strong risk factor for mortality.

CONCLUSIONS

After ASD surgery, the rates of minor complications, major complications, and mortality was 8.2%, 10.4%, and 0.6%, respectively. While mortality depended on patient physical status represented by the American Society of Anesthesiologists 4, minor and major complications were associated with male sex, dependent functional status, and surgical factors such as osteotomy procedure, prolonged operative time (>5 h), and having an anterior surgical approach. Therefore, this information may be helpful in surgical counseling and preoperative surgical planning.

摘要

研究设计

使用美国外科医师学会国家手术质量改进计划数据库进行回顾性队列分析。

目的

本研究旨在探讨成人脊柱畸形(ASD)手术患者围手术期并发症和死亡率的发生率和危险因素。

背景资料概要

尽管 ASD 手术与相对较高的并发症发生率相关,但很少有研究关注大型队列中的围手术期并发症。

材料和方法

在 2011-2013 年美国外科医师学会国家手术质量改进计划数据库的数据库中,通过主要和其他当前程序术语和国际疾病分类,第九修订版代码,确定了一组 20 岁以上接受 ASD 手术的患者队列(n=1484)。调查了围手术期(术后 30 天内)轻微/主要并发症和死亡率的发生率。使用逻辑回归模型评估轻微/主要并发症和死亡率的危险因素。

结果

在 1484 例接受 ASD 手术的患者中,总并发症发生率为 15.8%(轻微并发症:8.2%;主要并发症:10.4%),死亡率为 0.6%(9 例)。多变量分析后,依赖功能状态[P=0.003;比值比(ORs),4.838]、前路或前路+后路入路(P=0.001;OR,2.022)和手术时间延长(>5 小时)(P=0.004;OR,1.821)与轻微并发症风险增加相关。男性(P=0.013;OR,1.567)、截骨术(P=0.008;OR,1.674)和手术时间延长(>5 小时)(P<0.001;OR,2.142)与主要并发症风险增加相关。美国麻醉医师协会 4 级状态(P=0.009;OR,34.697)是死亡率的一个强危险因素。

结论

ASD 手术后,轻微并发症、主要并发症和死亡率的发生率分别为 8.2%、10.4%和 0.6%。虽然死亡率取决于患者的身体状况,由美国麻醉医师协会 4 级表示,但轻微和主要并发症与男性、依赖功能状态以及手术因素如截骨术、手术时间延长(>5 小时)和前路手术有关。因此,这些信息可能有助于手术咨询和术前手术计划。

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