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埃塞俄比亚南部阿尔巴明奇综合医院非创伤性急性腹痛外科住院患者肠梗阻的严重程度、模式和治疗结果。

Magnitude, pattern and management outcome of intestinal obstruction among non-traumatic acute abdomen surgical admissions in Arba Minch General Hospital, Southern Ethiopia.

机构信息

Department of Anatomy, Arba Minch University, Arba Minch, Ethiopia.

Departments of Physiology, Arba Minch University, Arba Minch, Ethiopia.

出版信息

BMC Surg. 2021 Jun 15;21(1):293. doi: 10.1186/s12893-021-01294-0.

Abstract

BACKGROUND

Intestinal obstruction is defined as a blockage or partial blockage of the passage of the intestinal contents. It is a potentially risky surgical emergency associated with high morbidity and mortality. Its pattern differs from country to country and even from place to place within a country. Therefore, this study aimed to find out the magnitude, pattern and management outcome of intestinal obstruction in Arba Minch General Hospital.

METHODS

A retrospective cross-sectional study was conducted in Arba Minch General hospital from January 09, 2015, to November 09, 2018. The data collection period was from December 15, 2018, to February 09, 2019. A simple random technique was applied to select 801 study participants. Then, the required data entered into Epi Info version 7.2.1.0 and exported to the statistical package for the social sciences software package version 20 for analysis. The binary logistic regression analysis has been done to determine crude statistical associations between independent variables and dependent variables. Linearity, Multivariate normality and multicollinearity were checked between independent and dependent variables by using scatter plot and Q-Q plot respectively. Variables with a p-value of less than 0.25 in the binary logistic regression analysis were entered into multivariable logistic regression. Statistical significance factors were identified based on a p-value of < 0.05 and with a 95% confidence interval.

RESULT

This study revealed that the overall magnitude of intestinal obstruction was 40.60% with 95% CI (34.95-45.95). The magnitude of unfavorable management outcomes and deaths during the study period were 22.3% with 95% CI (18.00-27.00) and 7.1% with 95% CI (4.00-10.00) respectively. Persistent tachycardia 10.3 (3.28-32.42), Dehydration 13.7 (3.34-56.56), elevated serum creatinine 10.2 (1.89-54.94), gangrenous small bowel volvulus 2.7 (1.27-5.84), ischemic bowel 3.4 (1.17-9.81) and perforated bowl 7.68 (2.96-19.93) were significantly associated with the management outcome of intestinal obstruction.

CONCLUSION AND RECOMMENDATION

Intestinal obstruction was the most common among all acute abdomen cases and its management outcome highly associated with dehydration. Adequate early preoperative resuscitation and proper post-operative care with appropriate surgical techniques and wound care with sterile techniques would help to reduce further mortality. This could be achieved by increasing public awareness of health-seeking behavior. Moreover, health facilities capable of handling patients with small bowel obstruction should be available within the reach of the community.

摘要

背景

肠梗阻是指肠道内容物的阻塞或部分阻塞。它是一种潜在危险的外科急症,与高发病率和死亡率相关。其模式因国家而异,甚至在一个国家内的不同地区也有所不同。因此,本研究旨在了解阿尔巴明奇总医院肠梗阻的规模、模式和管理结果。

方法

本研究是 2015 年 1 月 9 日至 2018 年 11 月 9 日在阿尔巴明奇总医院进行的回顾性横断面研究。数据收集期为 2018 年 12 月 15 日至 2019 年 2 月 9 日。采用简单随机技术选择 801 名研究参与者。然后,所需数据输入 Epi Info 版本 7.2.1.0,并导出到统计软件包版本 20 进行分析。采用二元逻辑回归分析确定独立变量和因变量之间的粗统计关联。通过散点图和 Q-Q 图分别检查独立变量和因变量之间的线性、多变量正态性和多重共线性。在二元逻辑回归分析中 p 值小于 0.25 的变量被纳入多变量逻辑回归。基于 p 值<0.05 和 95%置信区间确定有统计学意义的因素。

结果

本研究显示,肠梗阻的总体发生率为 40.60%,95%置信区间为(34.95-45.95)。研究期间,不良管理结果和死亡的发生率分别为 22.3%,95%置信区间为(18.00-27.00)和 7.1%,95%置信区间为(4.00-10.00)。持续心动过速 10.3(3.28-32.42)、脱水 13.7(3.34-56.56)、血清肌酐升高 10.2(1.89-54.94)、绞窄性小肠扭转 2.7(1.27-5.84)、缺血性肠病 3.4(1.17-9.81)和穿孔肠 7.68(2.96-19.93)与肠梗阻的管理结果显著相关。

结论和建议

肠梗阻是所有急腹症中最常见的,其管理结果与脱水高度相关。充分的早期术前复苏和适当的术后护理,结合适当的手术技术和伤口护理,采用无菌技术,将有助于降低进一步的死亡率。这可以通过提高公众对求医行为的认识来实现。此外,应该在社区能够到达的范围内提供能够处理小肠梗阻患者的卫生设施。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f2d9/8204523/0466c4d9995f/12893_2021_1294_Fig1_HTML.jpg

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